116140-20-6Relevant articles and documents
Catalytic N-Acylation of Cyclic Amines by Arylglyoxylic Acids via Radical-Radical Cross-Coupling
Bhadra, Sukalyan,Gupta, Aniket,Kumar Singh, Anupam,Rahaman, Ajijur
supporting information, p. 2198 - 2202 (2021/07/22)
A methodical mechanistic investigation allowed for the catalytic N-acylation of secondary cyclic amine counterparts by arylglyoxylic acids through radical-radical coupling. The reaction proceeds via a twofold SET-promoted Cu(I)/Cu(II) catalytic cycle under mild conditions. An analogous reaction variant allows for the N-acylation in a one-pot fashion directly starting from a secondary cyclic amine even in the presence of a second amine or hydroxy group.
Alkoxycarbonylpiperidines as N-nucleophiles in the palladium-catalyzed aminocarbonylation
Takacs, Attila,Kabak-Solt, Zsuzsanna,Mikle, Gabor,Kollar, Laszlo
, p. 1473 - 1478 (2014/10/15)
Piperidines possessing ester functionality, such as 2-(methoxycarbonyl) piperidine (methyl pipecolinate), 3-(ethoxycarbonyl)piperidine (ethyl nipecotate), and 4-(ethoxycarbonyl)piperidine (ethyl isonipecotate), were used as N-nucleophiles in palladium-cat
Asymmetric hydrogenation of pyridines: Enantioselective synthesis of nipecotic acid derivatives
Lei, Aiwen,Chen, Mao,He, Minsheng,Zhang, Xumu
, p. 4343 - 4347 (2007/10/03)
An asymmetric hydrogenation process of 3-substituted pyridine derivatives has been developed with the use of a Rh-TangPhos complex as the catalyst. The whole process consists of an efficient partial hydrogenation of nicotinate and a subsequent highly enan
