116163-87-2

Upstream product

• 110-00-9 furan 
• 75-89-8 2,2,2-trifluoroethanol 
• 116145-26-7 1-bromo-1-(2',3',4'-trimethoxyphenyl)propan-2-one 
• 116145-27-8 1-bromo-1-(5'-bromo-2',3',4'-trimethoxyphenyl)propan-2-one 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 81148-83-6 (E/Z)-2',3',4'-trimethoxy-1-propenylbenzene 
• 102119-67-5 1-(2',3',4'-trimethoxyphenyl)-2-propanone 
• 116145-29-0 1-(2',3',4'-trimethylphenyl)-1,2-epoxypropane 

Downstream Products

• 116145-42-7 1-(5-Bromo-2,3,4-trimethoxy-phenyl)-3-furan-2-yl-propan-2-one 

Relevant academic research and scientific papers

SYNTHESIS AND REACTIONS OF 2-ARYL-8-OXABICYCLOOCT-6-EN-3-ONES

A number of 1-aryl-1-bromopropanones have been prepared and converted into the corresponding oxyallyl carbocations.These were reacted with furan to produce the expected 2-aryl-8-oxabicyclooct-6-en-3-ones, as well as a number of interesting side-products.These included 3-aryl-propanoic acid esters produced via Favorskii rearrangements.Attempts to cleave the ether linkage in the cycloadducts using bromotrimethylsilane produced instead 1-aryl-3-furylpropanones in excellent yield.