116238-58-5Relevant academic research and scientific papers
Investigation of synthesis and some properties of the copper complexes containing imidazole ligand
Erdem, Emin,Akarsu, Mehri,Kilin?arslan, Rafet,Kaya?il, Ismail,Kara, Izzet,S?yleyici, Sevil
, p. 55 - 64 (2016/07/15)
The copper(II) complexes bearing tetrasubstituted imidazole derivatives containing oxygen donor as ligands (L1-6) were synthesized and characterized by spectroscopic methods, magnetic measurements, elemental and thermogravimetric analyses. The
A three-way switchable process for suzuki cross-coupling, hydrodehalogenation, or an assisted tandem hydrodehalogenation and suzuki cross-coupling sequence
Sandtorv, Alexander H.,Bjorsvik, Hans-Rene
supporting information, p. 3231 - 3243 (2013/12/04)
A three-way switchable Pd-catalyzed and microwave assisted process appropriate for selective arylation or hydrodehalogenation of the imidazole backbone was discovered and entirely optimized. The "arylation switch position" was adapted and optimized for the synthesis of 4,5-diaryl-1H-imidazoles, while the "hydrodehalogenation switch position" was used for the preparation of 4(5)-iodo-1H-imidazole. The hydrodehalogenation and the cross-coupling reactions were also successfully combined in "the third switch position" that performs an assisted tandem reaction sequence that produced 4(5)-aryl-1H-imidazole. All of the three pathways produced their corresponding products in excellent yield. Copyright
Synthesis of some 2,3,6,8-tetraarylimidazo[1,2-a]pyrazine derivatives by using either reflux or microwave irradiation method, and investigation their anticancer activities
Kayagil, Ismail,Demirayak, Seref
scheme or table, p. 13 - 24 (2011/12/22)
In this study, some 2,3,6,8-tetraarylimidazo[1,2-a]pyrazine derivatives were synthesized by reacting 1-(2-aryl-2-oxoethyl)-2-aryloyl-4,5- diarylimidazoles from 2-aryloyl-4,5-diarylimidazole and 2-bromoacetophenone derivatives with ammonium acetate in acetic acid by using the method that was previously developed and repeatedly tested in our studies. Structural elucidation of the compounds was performed by IR, 1H-NMR, and MASS spectroscopic data and elemental analysis results. Anticancer activities of selected compounds were evaluated and the noticeable activity values were reported.
