3457-48-5

Basic information

• Product Name: 4,4'-DIMETHYLBENZIL
• Synonyms: 1,2-Bis(4-methylphenyl)-1,2-ethanedione;1,2-Di-p-tolyl-ethane-1,2-dione;di-p-tolylethanedione;Ethanedione, bis(4-methylphenyl)-;Ethanedione,bis(4-methylphenyl)-;LABOTEST-BB LT00159323;4,4'-DIMETHYLDIBENZOYL;4,4'-DIMETHYLBENZIL
• CAS NO: 3457-48-5
• Molecular Formula: C₁₆H₁₄O₂
• Molecular Weight: 238.28
• EINECS: 222-388-2
• Product Categories: Aromatic Ketones (substituted);Benzil and Benzoin Compounds;Organic Photoinitiators;Polymerization Initiators
• Mol File: 3457-48-5.mol
• Article Data: 170

Chemical Properties

• Melting Point: 102-104 °C(lit.)
• Boiling Point: 211 °C (7 mmHg)
• Flash Point: 168.6 °C
• Appearance: yellow crystals or needles
• Density: 1.119±0.06 g/cm3 (20 ºC 760 Torr)
• Refractive Index: 1.6290 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4,4'-DIMETHYLBENZIL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DIMETHYLBENZIL(3457-48-5)
• EPA Substance Registry System: 4,4'-DIMETHYLBENZIL(3457-48-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36/37-26
• WGK Germany: 3
• Hazardous Substances Data: 3457-48-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 95, p. 1296, 1973 DOI: 10.1021/ja00785a047Tetrahedron Letters, 34, p. 3897, 1993 DOI: 10.1016/S0040-4039(00)79257-4

Upstream product

• 79-37-8 oxalyl dichloride 
• 108-88-3 toluene 
• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 874-60-2 4-methyl-benzoyl chloride 
• 99648-32-5 tetrakis(4-methylphenyl)-1,4-dioxine 
• 106675-70-1 N¹,N²-dimethoxy-N¹,N²-dimethyloxalamide 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 38424-23-6 (E)-4,4'-dimethylstilbene 
• 874-58-8 4-methylbenzoyl bromide 
• 611-97-2 bis(p-methylphenyl)-methanone 
• 68-12-2 N,N-dimethyl-formamide 
• 72487-29-7 (Z)-1,2,3,4-tetrakis(4-methylphenyl)-2-butene-1,4-dione 
• 51490-06-3 1,2-di-p-tolyl-ethanone 
• 64-10-8 phenyl carbamate 

Downstream Products

• 100-52-7 benzaldehyde 
• 99-94-5 p-Toluic acid 
• 134-81-6 benzil 
• 65-85-0 benzoic acid 
• 87234-40-0 p,p'-Dimethylstilbene-1,2-di(ethyl carbonate) 
• 123316-66-5 4-p-Bromophenyl-1,2-di-p-tolylbut-2-ene-1,4-dione 
• 123351-48-4 3a,6a-bis(p-tolyl)thioglycoluril 
• 30502-49-9 2-thioxo-5,5-di-p-tolylimidazolidin-4-one 
• 90833-49-1 2,3-bis(4-methylphenyl)-6-quinoxalinecarboxylic acid 
• 5173-28-4 (1R,2S)-1,2-Di-p-tolyl-ethane-1,2-diol 
• 41140-00-5 3,6-dimethyl-9H-fluoren-9-one 
• 190435-92-8 1,6-bis(p-methoxybenzyl)-7,8-di-p-tolylglycoluril 

Relevant articles and documents

Electrochemical oxidation-induced benzyl C–H carbonylation for the synthesis of aromatic α-diketones

Electrochemical oxidation-induced direct carbonylation of benzyl C–H bond for the synthesis of aromatic α-diketones is described. In this process, tetrabutylammonium iodide (nBu4NI) not only acts as an electrolyte, but its iodine anion is oxidized to an iodine radical at the anode, acting as a hydrogen atom transfer agent. The iodine radical extracts the benzyl hydrogen atom and causes the carbonylation of the benzyl position, where O2 in the air is used as an oxygen source.

Visible-Light-Induced Photocatalytic Oxidative Decarboxylation of Cinnamic Acids to 1,2-Diketones

A concerted metallophotoredox catalysis has been realized for the efficient decarboxylative functionalization of α,β-unsaturated carboxylic acids with aryl iodides in the presence of perylene bisimide dye to afford 1,2-diketones.

1-butyl-3-methylimidazol-2-ylidene as an efficient catalyst for cross-coupling between aromatic aldehydes and N-aroylbenzotriazoles

Cross-coupling of aromatic aldehydes with N-aroylbenzotriazoles in [Bmim]Br in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) provided an efficient procedure for the synthesis of 1,2-diarylethane-1,2-diones.