116255-96-0

Upstream product

• 75-15-0 carbon disulfide 
• 107-14-2 chloroacetonitrile 
• 109-77-3 malononitrile 
• 74-88-4 methyl iodide 
• 72436-89-6 4-Amino-3-methylsulfanyl-thieno[2,3-c]isothiazole-5-carbonitrile 

Downstream Products

• 119754-42-6 3-Chloro-5-phenylsulfanyl-thiophene-2,4-dicarbonitrile 
• 116170-88-8 2,4-dicyano-5-methylthio-3-phenylthiothiophene 
• 119754-50-6 2,4-dicyano-3,5-diphenylthiothiophene 

Relevant academic research and scientific papers

Thio compounds having fungicidal activity

The invention relates to new thio compounds of the general formula STR1 wherein R is an alkyl group substituted or not substituted with halogen and having 1-12 carbon atoms, an alkenyl or alkynyl group having 2-4 carbon atoms, an alkadienyl group having 3 or 4 carbon atoms or a substituted or unsubstituted phenyl or phenyl(C1 -C4)alkyl group; R1 is a cyano group, a formyl group, an alkylcarbonyl or alkoxycarbonyl group substituted or unsubstituted with halogen and having 2-5 carbon atoms, a substituted or unsubstituted benzoyl group, or an alkylsulphonyl group having 1-4 carbon atoms; R2 is a hydrogen atom, a halogen atom, an amino group unsubstituted or substituted with one or two groups selected from C1 -C4 alkyl and C2 -C5 alkylcarbonyl, an amino group forming part of a heterocyclic ring which may comprise 1 or 2 additional heteroatoms selected from N, O and S, an alkyl or alkoxy group having 1-4 carbon atoms and optionally substituted with C2 -C5 alkylcarbonyl, or a substituted or unsubstituted phenyl, phenoxy or phenylthio group; or wherein R1 and R2, together with the vinylene group to which they are bound, constitute a substituted or unsubstituted phenyl group; X is a cyano group or a formyl group; n is 1 or 2; Y is an alkylthio group having 1-4 carbon atoms; and Z is a hydrogen atom, a halogen atom, a nitro group, or an alkyl or alkoxy group having 1-4 carbon atoms and optionally substituted with halogen; or wherein Y and Z together constitute a sulphur atom; with the proviso that, when Y and Z do not together constitute a sulphur atom, R1 and R2, together with the vinylene group to which they are bound, constitute a substituted or unsubstituted phenyl group. The new compounds show a fungicidal and/or bactericidal activity and may be used in particular against plantpathogenic seed fungi and soil fungi and/or bacteria.

THE LIGHT INDUCED CONVERSION OF THIENOISOTHIAZOLES INTO THIOPHENES

The sun light induced conversion of thienoisothiazoles 1a-d into thiophenes 2a-d with loss of elemental sulfur is reported.A presumable mechanism for the thiophene nucleus formation is discussed to involve the opening of the two heterocyclic rings with formation of an open-chain valence bond isomer through the initial homolytic cleavage of the isothiazole N-S linkage.

THE SYNTHESIS OF 2-(ALKYLTHIO)- AND 2-(ARYLTHIO)-3-CYANOTHIOPHENES. THE NUCLEOPHILIC DISPLACEMENT OF THE ALKYLSULFINYL GROUP BY THIOLS.

The nucleophilic substitution of activated 2-(alkylsulfinyl)thiophenes with alkyl- or arylmercaptans gives the corresponding 2-(alkylthio)- or 2-(arylthio)- substituted thiophenes.When thiolate anion is used instead of thiol, sulfoxide reduction is the ma