1163-50-4Relevant academic research and scientific papers
One-pot synthesis of homotryptamines from indoles
Denhart, Derek J.,Mattson, Ronald J.,Ditta, Jonathan L.,Macor, John E.
, p. 3803 - 3805 (2004)
A method is presented for the one-pot synthesis of homotryptamines by the MacMillan reaction of indoles with acrolein followed by reductive amination.
Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs)
Schmitz, William D.,Denhart, Derek J.,Brenner, Allison B.,Ditta, Jonathan L.,Mattson, Ronald J.,Mattson, Gail K.,Molski, Thaddeus F.,Macor, John E.
, p. 1619 - 1621 (2005)
A series of N,N-dimethylhomotryptamines was prepared and their binding affinities at the serotonin transporter (SERT) were determined. Compounds possessing an electron withdrawing substituent at the C5-position of the indole nucleus were found to be poten
