116325-48-5

Usage

Derivative of indole

Heterocyclic organic compound

Unique chemical properties

Due to the presence of a phenylsulfonyl group on the indole ring

Use in organic synthesis

As a precursor to various pharmaceuticals and agrochemicals

Potential for introducing new functional groups

onto the indole core

Studied for biological activities

Including its role as an inhibitor of certain enzymes

Potential drug candidate

In the treatment of various diseases

Upstream product

• 91-55-4 2,3-dimethylindole 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 164261-56-7 1-(Phenylsulfonyl)-3-methyl-2-(bromomethyl)indole 
• 1026938-03-3 (3-methyl-1-(phenylsulfonyl)-1H-indol-2-yl)methanol 
• 856111-22-3 1-benzenesulfonyl-2-methyl-3-phenylsulfanylmethyl-1H-indole 
• 856111-10-9 1-benzenesulfonyl-3-methyl-2-phenylsulfanylmethyl-1H-indole 
• 477952-94-6 2-i-propyl-4-(phenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[3,4-b]indole 
• 477952-93-5 2-tert-butyl-4-(phenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[3,4-b]indole 
• 477952-95-7 2-benzyl-4-(phenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[3,4-b]indole 
• 477952-96-8 2-(p-methoxybenzyl)-4-(phenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[3,4-b]indole 
• 168838-44-6 3-methyl-1-phenylsulfonyl-2-<β(3',4'-dimethoxyphenyl)vinyl>indole 
• 168838-38-8 diethyl<(1-phenylsulfonyl)-3-methylindol-2-yl>methyl phosphonate 

Relevant academic research and scientific papers

The generation of Indole-2,3-quinodimethanes from the Deamination of 1,2,3,4-Tetrahydropyrrolo[3,4-b]indoles

A novel generation of indole-2,3-quinodimethanes via the deamination of 1,2,3,4-tetrahydropyrrolo[s3,4-b]indoles is reported.

Synthesis of N-substituted pyrrolo[3,4-b]indoles from 2,3-dimethylindole

Pyrrolo[3,4-b]indoles 8 are conveniently synthesized from 2,3-dimethylindole (4) in four steps, the last of which is DDQ oxidation of dihydropyrrolo[3,4-b]indoles 7 (85-98% yield).

A Versatile Construction of the 8H-Quinocarbazole Ring System as a Potential DNA Binder

A short synthesis of the quino- and quinocarbazoles is repoerted.The key step of the synthesis involves the preparation of suitable 2,3-divinylindoles by consecutive Wittig reactions.The thermal electrocyclic reaction of the divinylindole wi

Unusual oxidation of 2 (or 3)-methylindole derivatives with active manganese dioxide

Oxidation of 15-methoxy-1-phenylsulfonyl-2-methyl indole-3-aldehyde (3) with active manganese dioxide to the corresponding indole-2,3-dialdehyde (4) and similar reactions are reported.

Synthesis of 3-aryl-5H-pyrido[4,3-b]indoles

3-aryl-γ-carbolines (8) were synthesized by the thermal decomposition of 3-azidomethyl-2-(β-arylvinyl)-1-phenylsulfonyl indole (6).