1163732-89-5 Usage
Uses
Used in Biochemical Research:
Biotin-PEG5-azide is used as a biotinylation agent for the modification of biomolecules such as proteins, peptides, and nucleic acids. The biotinylation process enables the specific recognition and detection of these molecules using streptavidin-based assays, facilitating their study in various research applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Biotin-PEG5-azide can be used as a component in the design of targeted drug delivery systems. The biotinylation of drug molecules or carriers with Biotin-PEG5-azide can enhance their specificity towards certain cell types or tissues, potentially improving the efficacy and reducing the side effects of the treatment.
Used in Diagnostics:
Biotin-PEG5-azide is used as a labeling agent in the development of diagnostic tools, such as immunoassays and biosensors. The stable biotin-streptavidin interaction ensures a strong signal amplification, leading to increased sensitivity and accuracy in detecting various biomarkers.
Used in Molecular Biology:
In molecular biology, Biotin-PEG5-azide can be employed for the construction of molecular complexes and the study of molecular interactions. The biotinylation of specific molecules allows for their immobilization on solid supports, enabling the investigation of their binding properties and interactions with other biomolecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1163732-89-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,3,7,3 and 2 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1163732-89:
(9*1)+(8*1)+(7*6)+(6*3)+(5*7)+(4*3)+(3*2)+(2*8)+(1*9)=155
155 % 10 = 5
So 1163732-89-5 is a valid CAS Registry Number.
1163732-89-5Relevant academic research and scientific papers
Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Im, Eun-Ju,Lee, Chan-Hyeong,Moon, Pyong-Gon,Rangaswamy, Gunassekaran Gowri,Lee, Byungheon,Lee, Jae Man,Lee, Jae-Chul,Jee, Jun-Goo,Bae, Jong-Sup,Kwon, Taeg-Kyu,Kang, Keon-Wook,Jeong, Myeong-Seon,Lee, Joo-Eun,Jung, Hyun-Suk,Ro, Hyun-Joo,Jun, Sangmi,Kang, Wonku,Seo, Seung-Yong,Cho, Young-Eun,Song, Byoung-Joon,Baek, Moon-Chang
, (2019/04/01)
Inhibitors of the secretion of cancer exosomes, which promote cancer progression and metastasis, may not only accelerate exosome biology research but also offer therapeutic benefits for cancer patients. Here we identify sulfisoxazole (SFX) as an inhibitor
Role of linkers in tertiary amines that mediate or catalyze 1,3,5-triazine-based amide-forming reactions
Kitamura, Masanori,Kawasaki, Fumitaka,Ogawa, Kouichi,Nakanishi, Shuichi,Tanaka, Hiroyuki,Yamada, Kohei,Kunishima, Munetaka
supporting information, p. 3709 - 3714 (2014/05/06)
We studied 1,3,5-triazine-based amide-forming reactions that are mediated or catalyzed by various tert-amines. The representative tert-amine was trimethylamine, which has amido, 1,2,3-triazolyl, aryl, and alkyl linkers. It was found that electron-deficient aryl and heteroaryl linkers, particularly 1,2,3-triazolyl linkers, are superior. On the basis of our findings, we synthesized ligand catalysts, including a 1,2,3-triazolyl linker that connects a protein ligand to a trimethylamine moiety, and found that fluorescent-labeling of a targeting protein using the ligand catalysts proceeded in good yields.
