116444-16-7Relevant academic research and scientific papers
Asymmetric total synthesis of filamentous fungi related resorcylic acid lactones 7-epi-zeaenol and zeaenol
Doda, Sai Reddy,Raghavendar, Avula,Haridasyam, Sharath Babu,Putta, Chandra Shekar,Rao, Bhattu Kanakadurga,Kadari, Sudhakar
, p. 78 - 84 (2019/06/06)
An efficient, short and, a convenient asymmetric total synthesis of filamentous fungi related resorcylic acid lactones 7-epi-zeaenol (2) and zeaenol (1) have been achieved in 7 and 9 linear steps with the high overall yield of 32% and 21% respectively, from the known intermediate 13. Mitsunobu inversion, De Brabander's protocol for macrolactonisation, Heck cross-coupling, diastereoselective alkyne aldehyde coupling and Ohira-Bestmann alkynylation are the key reactions.
Asymmetric synthesis of Goniothalesdiol A from (R)-2,3-O-cyclohexylidine glyceraldehyde
Venkataiah, Mallam,Somaiah, Palabindela,Reddipalli, Gowrisankar,Fadnavis, Nitin W.
experimental part, p. 2230 - 2233 (2010/03/03)
Goniothalesdiol A 1 has been synthesized from (R)-2,3-O-cyclohexylidine glyceraldehyde with high stereoselectivity and 22% overall yield in 11 simple steps. The key features of the synthetic strategy include the stereocontrolled allylation of (R)-2,3-O-cy
