116451-10-6

Upstream product

• 107-10-8 propylamine 
• 86489-95-4 2,5-dimethoxy-3,4-dimethylbenzaldehyde 

Downstream Products

• 113726-75-3 (2S,3S)-3-(2,5-Dimethoxy-3,4-dimethyl-phenyl)-2-propyl-oxaziridine 
• 113726-76-4 (2R,3S)-3-(2,5-Dimethoxy-3,4-dimethyl-phenyl)-2-propyl-oxaziridine 
• 113726-92-4 2,3-Dimethyl-5-((2S,3S)-2-propyl-oxaziridin-3-yl)-[1,4]benzoquinone 
• 113726-93-5 2,3-Dimethyl-5-((2R,3S)-2-propyl-oxaziridin-3-yl)-[1,4]benzoquinone 

Relevant academic research and scientific papers

Synthesis of Oxaziridinylquinones and Oxaziridinylazines as Potential Antitumor Agents

1,4-Benzoquinones, 1,4-naphthoquinones, as well as pyridines and quinolines having 2-alkyloxaziridinyl substituents were synthesized.The method involves formation of aldimines and their oxidation to oxaziridines. 1,4-Dimethoxyarenes bearing oxaziridinyl substituents were converted into the corresponding quinones with silver(II) dipicolinate.Some of the oxaziridinylquinones and -azines exhibit activity against KB cells, and the structure-activity relationship is discussed in terms of the current theory of biologically activated alkylating agents.

Synthesis of 2-Alkyl-3-aryloxaziridines

A convenient method for the synthesis of 2-alkyl-3-aryloxaziridines 1 based on the formation of stable azomethines and their oxidation with m-chloroperoxybenzoic acid is reported.The scope and limitation of the method proposed is illustrated with numerous