116518-98-0Relevant articles and documents
Thiazolidinedione derivatives and pharmaceutical compositions containing same
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Paragraph 0290-0295, (2021/01/24)
The present invention relates to thiazolidinedione derivatives and pharmaceutical compositions comprising the same. Specifically, the compounds disclosed by the invention have a structure shown as a formula (I), and the definitions of all groups and subst
Synthesis and structure-activity relationship studies of cinnamic acid-based novel thiazolidinedione antihyperglycemic agents
Neogi, Partha,Lakner, Fredrick J.,Medicherla, Satyanarayana,Cheng, Jin,Dey, Debendranath,Gowri, Maya,Nag, Bishwajit,Sharma, Somesh D.,Pickford, Lesley B.,Gross, Coleman
, p. 4059 - 4067 (2007/10/03)
A number of 2,4-thiazolidinedione derivatives of -phenyl substituted cinnamic acid were synthesized and studied for their PPAR agonist activity. The E-isomer of cinnamic acid, 11, showed moderate PPAR transactivation. The corresponding Z-isomer, 23, and d
Novel Heterocyclic analogs of diphenylethylene compounds
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, (2008/06/13)
Novel diphenylethylene compounds containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. In co