116599-39-4

Basic information

• Product Name: 4-CHLORO-3-NITROBENZYLAMINE HYDROCHLORIDE
• Synonyms: 4-CHLORO-3-NITROBENZYLAMINE HYDROCHLORIDE;(4-chloro-3-nitrophenyl)methanamine:hydrochloride
• CAS NO: 116599-39-4
• Molecular Formula: C₇H₇ClN₂O₂*ClH
• Molecular Weight: 223.06
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 116599-39-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CHLORO-3-NITROBENZYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3-NITROBENZYLAMINE HYDROCHLORIDE(116599-39-4)
• EPA Substance Registry System: 4-CHLORO-3-NITROBENZYLAMINE HYDROCHLORIDE(116599-39-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 116599-39-4(Hazardous Substances Data)

Upstream product

• 939-80-0 4-chloro-3-nitrobenzonitrile 

Downstream Products

• 1242269-27-7 N-(4-chloro-3-nitro-benzyl)-1-trifluoromethyl-cyclopropane carboxamide 
• 1380919-26-5 N-{4-chloro-3-[3-methyl-6-(4-trifluoromethyl-piperidin-1-yl)-1H-benzimidazol-2-ylamino]-benzyl}-2,2-dimethyl-propionamide 
• 1380921-23-2 N-(4-chloro-3-{3-[2-methylamino-5-(4-trifluoromethyl-piperidin-1-yl)-phenyl]-thioureido}-benzyl)-2,2-dimethyl-propionamide 
• 1380921-13-0 {4-chloro-3-[5-chloro-6-(2-dimethylaminomethyl-pyrrolidin-1-yl)-1H-benzimidazol-2-ylamino]-benzyl}-carbamic acid tert-butyl ester 
• 1380919-20-9 N-{4-chloro-3-[5-chloro-6-(2-dimethylcarbamoyl-pyrrolidin-1-yl)-1H-benzimidazol-2-ylamino]-benzyl}-2,2-dimethyl-propionamide 
• 1380921-06-1 {3-[6-(5-aza-spiro[2.4]hept-5-yl)-5-chloro-1H-benzimidazol-2-ylamino]-4-chloro-benzyl}-carbamic acid tert-butyl ester 
• 1380919-17-4 N-{4-chloro-3-[5-chloro-6-(3-dimethylaminomethyl-pyrrolidin-1-yl)-1H-benzimidazol-2-ylamino]-benzyl}-2,2-dimethyl-propionamide 
• 1380921-03-8 4-chloro-3-[5-chloro-6-(3-dimethylaminomethyl-pyrrolidin-1-yl)-1H-benzimidazol-2-ylamino]-benzylamine 
• 1380921-02-7 N-{4-chloro-3-[5-chloro-6-(3-dimethylaminomethyl-pyrrolidin-1-yl)-1H-benzimidazol-2-ylamino]-benzyl}-carbamic acid tert-butyl ester 
• 1380919-16-3 N-{4-chloro-3-[6-chloro-5-(3,3-difluoropyrrolidin-1-yl)-1H-benzo[d]imidazol-2-ylamino]benzyl}-2,2-dimethyl-propionamide 
• 1380920-96-6 4-chloro-3-[5-chloro-1-methyl-6-(3-(trifluoromethyl)piperidin-1-yl)-1H-benzo[d]imidazol-2-ylamino]benzylamine 
• 1380920-95-5 tert-butyl N-{4-chloro-3-[5-chloro-1-methyl-6-(3-(trifluoromethyl) piperidin-1-yl)]-1H-benzo[d]imidazol-2-ylaminolbenzyl}-carbamate 
• 180081-29-2 N-(4-chloro-3-nitrophenylmethyl)carbamic acid t-butyl ester 
• 1360702-27-7 N-(4-chloro-3-nitrobenzyl)-2,2-dimethyl-propionamide 

Relevant articles and documents

TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS

The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.