116627-59-9

Basic information

• Product Name: (4S,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-iodomethyl-tetrahydro-pyran-2-one
• CAS NO: 116627-59-9
• Molecular Weight: 494.445
• Mol File: 116627-59-9.mol

Chemical Properties

• CAS DataBase Reference: (4S,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-iodomethyl-tetrahydro-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-iodomethyl-tetrahydro-pyran-2-one(116627-59-9)
• EPA Substance Registry System: (4S,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-iodomethyl-tetrahydro-pyran-2-one(116627-59-9)

Safety Data

• Hazardous Substances Data: 116627-59-9(Hazardous Substances Data)

Upstream product

• 116643-37-9 (3S)-3-hydroxyglutaric acid monopropyl ester 
• 116627-54-4 C₄₀H₅₀O₅Si₂ 
• 116643-38-0 (3S)-3-tert-butyldiphenylsiloxyglutaric acid monopropyl ester 
• 116627-55-5 (3S)-5-hydroxy-3-tert-butyldiphenylsiloxypentanoic acid propyl ester 
• 116627-56-6 (3S)-5-oxo-3-tert-butyldiphenylsiloxypentanoic acid propyl ester 
• 116627-57-7 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-hex-5-enoic acid propyl ester 
• 53630-64-1 dipropyl 1,3-acetonedicarboxylate 
• 116627-53-3 3-Hydroxy-pentanedioic acid dipropyl ester 
• 542-05-2 acetonedicarboxylic acid 
• 116627-58-8 (3S)-3-hex-5-enoic acid 

Relevant articles and documents

SYNTHESES OF 4(R)-SILYLOXY-6(S)-IODOMETHYL-TETRAHYDROPYRAN-2-ONE AND ITS ENANTIOMER, BUILDING BLOCKS FOR HMG-COA REDUCTASE INHIBITORS

Optically pure 4(R),6(S)-iodolactone 1 was obtained from α-D-(+)-glucose in 17 steps with 17percent overall yield.Its enantiomer 4(S),6(R)-iodolactone 1' was obtained from acetonedicarboxylic acid in 9 steps in 37percent overall yield and with 70percent e