116645-15-9

Upstream product

• 116645-14-8 5-(4-fluorophenyl)-3-(1-methylethyl)-1-phenyl-1H-pyrazole-4-propanal 
• 105-45-3 acetoacetic acid methyl ester 
• 114433-94-2 1-(4-Fluorophenyl)-3-isopropylpropan-1,3-dione 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 116645-24-0 4-<2-(1,3-dioxolan-2-yl)ethyl>-5-(4-fluorophenyl)-3-(1-methylethyl)-1-phenyl-1H-pyrazole 
• 116645-13-7 2-<2-(1,3-dioxolan-2-yl)ethyl>-1-(4-fluorophenyl)-4-methyl-1,3-pentanedione 

Downstream Products

• 116645-11-5 R*,R*-5-(4-fluorophenyl)-β,δ-dihydroxy-3-(1-methylethyl)-1-phenyl-1H-pyrazole-4-heptanoic acid 
• 116645-09-1 (+/-)-6-<2-<5-(4-fluorophenyl)-3-(1-methylethyl)-1-phenyl-1H-pyrazol-4-yl>ethyl>tetrahydro-4-hydroxy-2H-pyran-2-one 
• 124288-10-4 3-Benzyloxy-7-[5-(4-fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-5-hydroxy-heptanoic acid 
• 124288-09-1 (4S,6S)-4-Benzyloxy-6-{2-[5-(4-fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-ethyl}-tetrahydro-pyran-2-one 
• 124288-12-6 6-{2-[5-(4-fluorophenyl)-3-(1-methylethyl)-1-phenyl-1H-pyrazol-4-yl]ethyl}tetrahydro-4-methoxy-2H-pyran-2-one 
• 124288-08-0 6-<2-<5-(4-fluorophenyl)-3-(1-methylethyl)-1-phenyl-1H-pyrazol-4-yl>ethyl>-5,6-dihydro-2H-pyran-2-one 

Relevant academic research and scientific papers

Inhibitors of cholesterol biosynthesis. 2. 1,3,5-Trisbustituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles

A series of 1,3,5-trisubstituted pyrazole mevalonolactones were prepared and evaluated for their ability to inhibit the enzyme HMG-CoA reductase in vitro. Since previous studies suggested that the 5-(4-fluorophenyl) and 3-(1-methylethyl) substituents affo

Treating fungal infections with substituted-(6-(tetrahydro-4-hydroxy-2-oxo-2H-pyran-2-yl)ethyl)- or ethenyl)pyrazoles

A method of treating fungal infections in mammals employing 1,3,5-trisubstituted-4- (4-hydroxy-2-oxo-pyran-6-yl)pyrazoles is disclosed.