116659-69-9Relevant academic research and scientific papers
Copper-catalyzed intermolecular thioamination of maleimides with thiols and formamides: A one-step construction of 3-Amino-4-Thiomaleimides using formamides as nitrogen sources
Yang, Zhen-Hua,Zhu, Jia-Nan,Jin, Ze-Hui,Zheng, Jian,Zhao, Sheng-Yin
, p. 4627 - 4636 (2018)
A highly efficient copper-catalyzed intermolecular C(sp2)-H thioamination of maleimides with thiols and formamides in the presence of fluoroboric acid is reported using various readily available formamides as nitrogen sources and solvents. A diverse range of 3-Amino-4-Thiomaleimides is obtained with good yields under mild conditions, involving C-N and C-S bond formation. This methodology enriches current C-N and C-S bond formation chemistry and features operational simplicity and excellent functional-group tolerance.
Three-Component Coupling Reactions of Maleimides, Thiols, and Amines: One-Step Construction of 3,4-Heteroatom-functionalized Maleimides by Copper-Catalyzed C(sp2)?H Thioamination
Yang, Zhen-Hua,Tan, Hong-Ru,An, Yu-Long,Zhao, Yu-Wei,Lin, Hao-Peng,Zhao, Sheng-Yin
supporting information, p. 173 - 179 (2017/11/22)
A copper-catalyzed intermolecular thioamination of maleimides with thiols and amines has been developed. A diverse range of 3-amino-4-thiomaleimides and 3,4-dihydropyrrolo[3,4-b][1,4]thiazine-5,7(2H,6H)-diones were obtained with good yields, involving C?N and C?S bond formations. This methodology is very practical and features high atom economy, excellent functional group tolerance. (Figure presented.).
From furans to anilines: Toward one-pot two-step amination/Diels-Alder sequences
Medimagh, Raouf,Marque, Sylvain,Prim, Damien,Chatti, Saber,Zarrouk, Hedi
, p. 2191 - 2197 (2008/09/18)
(Chemical Equation Presented) Selective metal-free amination and Diels-Alder reactions are described in the furan series, leading to polysubstituted anilines or to stable oxabicyclic adducts in high yield. Interestingly, anilines are conveniently prepared through a novel one-pot, two-step amination/Diels-Alder procedure from commercially available 5-bromo-2-furaldehyde.
