3760-54-1

Basic information

• Product Name: 1-FORMYLPYRROLIDINE
• Synonyms: TIMTEC-BB SBB008020;N-FORMYLPYRROLIDINE;PYRROLIDINE-1-CARBOXALDEHYDE;1-PYRROLIDINECARBOXALDEHYDE;1-FORMYLPYRROLIDINE;1-Pyrrolidinecarbaldehyde;pyrrolidine-1-carbaldehyde;prolinal
• CAS NO: 3760-54-1
• Molecular Formula: C₅H₉NO
• Molecular Weight: 99.13
• EINECS: 223-175-7
• Mol File: 3760-54-1.mol
• Article Data: 110

Chemical Properties

• Boiling Point: 92-94 °C15 mm Hg(lit.)
• Flash Point: 203 °F
• Appearance: clear slightly yellow liquid
• Density: 1.04 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.71mmHg at 25°C
• Refractive Index: n20/D 1.479(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.44±0.20(Predicted)
• BRN: 106540
• CAS DataBase Reference: 1-FORMYLPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-FORMYLPYRROLIDINE(3760-54-1)
• EPA Substance Registry System: 1-FORMYLPYRROLIDINE(3760-54-1)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 3760-54-1(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR SLIGHTLY YELLOW LIQUID

Uses

1-Formylpyrrolidine was used in the synthesis of 1-oxa-3,4-dimethyl-5-(1-pyrrolldino)-2,2-di(tert-butyl)silacyclopentane and 1-oxa-4-isopropyl-5-(1-pyrrolidino)-2,2-di(tert-butyl)silacyclopentane.

General Description

1-Formylpyrrolidine is the monomer constituent of gas clathrate inhibitor.

InChI:InChI=1/C5H9NO/c7-4-5-2-1-3-6-5/h4-6H,1-3H2

Upstream product

• 123-75-1 pyrrolidine 
• 64-18-6 formic acid 
• 75-87-6 chloral 
• 50-00-0 formaldehyd 
• 67-66-3 chloroform 
• 18197-22-3 N-formylformamide 
• 201230-82-2 carbon monoxide 
• 77287-34-4 formamide 
• 110-83-8 cyclohexene 
• 109-94-4 formic acid ethyl ester 
• 6908-73-2 (E)-1-styrylpyrrolidine 
• 4625-58-5 Bis(1-pyrrolidinyl)acetonitril 
• 123-11-5 4-methoxy-benzaldehyde 
• 56176-56-8 E-1-pyrrolidino-1-butene 

Downstream Products

• 120-94-5 1-Methylpyrrolidine 
• 56951-49-6 1-[N-(5-nitro-[1,3,4]thiadiazol-2-yl)-formimidoyl]-pyrrolidine 
• 58415-03-5 C₉H₉NOS 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 86869-55-8 C₉H₁₀N₂OS 
• 119141-10-5 2,4-dichloro-3-(pyrrolidinylmethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde 
• 1817-49-8 1,3-diphenyl-1-propyn-3-ol 
• 85377-68-0 C₈H₆ClNOS 
• 5564-73-8 1-(dimethoxymethyl)pyrrolidine 
• 7632-86-2 1-p-methoxyphenyl-3-pyrrolidino-2-propen-1-thione 
• 3760-55-2 N-nitropyrrolidine 
• 87167-61-1 9-benzyl-1-methyl-9H-carbazole-3-carbaldehyde 
• 87167-64-4 (9-benzyl-1,2,3,4-tetrahydrocarbazol-1-yl)carboxaldehyde 
• 764-93-2 1-decyne 

Relevant articles and documents

Olefin functionalized IPr.HCl monomer as well as preparation method and application thereof

The invention relates to an olefin functionalized IPr.HCl monomer, a preparation method thereof, a method for preparing an N-heterocyclic carbene functionalized organic polymer (PS-IPr-x) by using the olefin functionalized IPr.HCl monomer, and application of the N-heterocyclic carbene functionalized organic polymer as a heterogeneous catalyst for catalyzing reduction N-formylation of carbon dioxide and amine. A heterogeneous catalyst is prepared by using cheap and easily available DVB as a polymerization cross-linking agent through an AIBN-initiated olefin polymerization method, and has the advantages of low preparation cost and simple preparation method. Meanwhile, the catalytic activity of the catalyst is obviously higher than that of reported catalysts, and the catalyst has a wide practical application prospect.

Nickel-Catalyzed Amination of Aryl Chlorides with Amides

A nickel-catalyzed amination of aryl chlorides with diverse amides via C-N bond cleavage has been realized under mild conditions. A broad substrate scope with excellent functional group tolerance at a low catalyst loading makes the protocol powerful for synthesizing various aromatic amines. The aryl chlorides could selectively couple to the amino fragments rather than the carbonyl moieties of amides. Our protocol complements the conventional amination of aryl chlorides and expands the usage of inactive amides.

Method for preparing formamide compound by using MCOF to catalyze CO2 as carbon source at normal temperature and pressure

The invention provides a method for preparing a formamide compound by using MCOF to catalyze CO2 as a carbon source at normal temperature and pressure, and belongs to the technical field of chemistry and chemical engineering. Under the conditions of normal temperature and normal pressure, CO2 is used as a carbon source to realize N-formylation reaction of various amine substrates. The method has the advantages that the reaction system uses the metal ion-doped two-dimensional covalent organic framework MCOF as the catalyst, CO2 is reduced at normal temperature and normal pressure to provide acyl, high-pressure hydrogen and toxic CO are prevented from being used, and the reaction conditions are mild (normal temperature and normal pressure). According to the method for preparing the formamide, the greenhouse gas carbon dioxide serves as a carbon source, the cost is low, operation is easy, reaction conditions are mild (normal temperature and normal pressure), the yield of the prepared formamide product is excellent (99%), and a green synthesis method is provided for N-acylation reaction.