116719-56-3

Upstream product

• 1056477-06-5 2-bromocyclohexanone 
• 116719-54-1 2-hydroxy-4-(2'-oxo-cyclohexyloxy)acetophenone 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 106920-99-4 1-(3-hydroxy-6,7,8,9-tetrahydrodibenzofuran-2-yl)-ethanone 
• 100-52-7 benzaldehyde 

Downstream Products

• 116719-64-3 2,3,4,5-tetrahydro-7-styryl-9H-benzofuro<3,2-g><1>benzopyran-9-one 
• 116719-60-9 4-cinnamoyl-3-hydroxydibenzofuran 

Relevant academic research and scientific papers

One-pot synthesis of furoflavanones

Several new furoflavanones (5-7) have been synthesized from hydroxy acetyl benzofuran and an aryl aldehyde in presence of piperidine. These furoflavanones were dehydrogenated to furoflavones (8-10) using DDQ (2,3-dichloro-5,6-dicyano- 1,4-benzoquinone). The chalcone synthesized (4b) using 1% ethanolic sodium hydroxide from hydroxy acetyl benzofuran and aryl aldehyde shows promising antiinflammatory activity.

A Facile Synthesis of 4-Cinnamoyl-dibenzofurans

A facile synthesis of 4-cinnamoyldibenzofuran derivatives has been achieved by condensation of 2-bromocyclohexanone with hydroxyacetophenons, ring closure with alkali followed by condensation with benzaldehyde and subsequent dehydrogenation with DDQ.