1167435-01-9Relevant academic research and scientific papers
Synthesis of spirocyclic σ1 receptor ligands as potential PET radiotracers, structure-affinity relationships and in vitro metabolic stability
Gro?e Maestrup, Eva,Wiese, Christian,Schepmann, Dirk,Hiller, Achim,Fischer, Steffen,Scheunemann, Matthias,Brust, Peter,Wünsch, Bernhard
, p. 3630 - 3641 (2009)
Several 3H-spiro[[2]benzofuran-1,4′-piperidines] bearing a p-fluorobenzyl residue at the N-atom and various substituents in position 3 of the benzofuran system were synthesized. The crucial reaction steps are the addition of a lithiated benzaldehyde deriv
