116911-32-1

Basic information

• Product Name: (S)-2-azido-3-phenylpropionic acid methyl ester
• Synonyms: (S)-2-azido-3-phenylpropionic acid methyl ester
• CAS NO: 116911-32-1
• Molecular Weight: 205.216
• Mol File: 116911-32-1.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: (S)-2-azido-3-phenylpropionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-azido-3-phenylpropionic acid methyl ester(116911-32-1)
• EPA Substance Registry System: (S)-2-azido-3-phenylpropionic acid methyl ester(116911-32-1)

Safety Data

• Hazardous Substances Data: 116911-32-1(Hazardous Substances Data)

Upstream product

• 27000-00-6 methyl 2-hydroxy-3-phenylpropionate 
• 182937-63-9 (R)-2-(benzyloxy)-3-phenylpropanoic acid 
• 67-56-1 methanol 
• 79410-35-8 (2S)-2-azido-3-phenylpropanoic acid 
• 13673-95-5 (S)-methyl 2-hydroxy-3-phenylpropanoate 
• 35016-63-8 (S)-2-bromo-3-phenylpropionic acid 
• 63-91-2 L-phenylalanine 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 124916-61-6 (S)-2-bromo-3-penylpropanoic acid methyl ester 
• 130608-06-9 (S)-methyl 2-((p-nitrobenzene)sulfonyl)oxy 3-phenylpropanoate 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 

Downstream Products

• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 872864-31-8 (S)-2-[4-((S)-1-tert-Butoxycarbonylamino-2-phenyl-ethyl)-[1,2,3]triazol-1-yl]-3-phenyl-propionic acid methyl ester 
• 1261352-19-5 3-{1-[(1S)-1-carboxy-2-phenylethyl]-1H-1,2,3-triazol-4-yl}-L-alanine hydrochloride 
• 1261352-22-0 3-{1-[(1S)-1-carboxy-2-phenylethyl]-1H-1,2,3-triazol-5-yl}-L-alanine hydrochloride 
• 1261352-29-7 C₁₉H₂₄N₄O₆ 
• 1261352-30-0 C₁₉H₂₄N₄O₆ 
• 1261352-25-3 N-(tert-butoxycarbonyl)-3-{1-[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]-1H-1,2,3-triazol-4-yl}-L-alanine 
• 1261352-28-6 methyl N-(tert-butoxycarbonyl)-3-{1-[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]-1H-1,2,3-triazol-5-yl}-L-alaninate 

Relevant articles and documents

A convenient synthesis of azido peptides by post-assembly diazo transfer on the solid phase applicable to large peptides

An efficient method for the conversion of solid phase bound peptide amines into azides by a diazo transfer using triflyl azide in the presence of divalent copper ions is described. α-Azido acids and azido peptides - up to 30 amino acids in length - are obtained in good yields and high purities after cleavage from the solid support.

Concise synthesis of: N -phosphorylated amides through three-component reactions

N-Phosphorylated amides continue to be an unparalleled asset for the development of pharmaceutical molecules, and the importance of this framework has inspired researchers to look for concise and efficient methods for the synthesis of this unit. In this work, a new strategy was developed in which a one-pot synthesis of N-phosphorylated amides was achieved by a three-component reaction with carboxylic acids, phosphorus chlorides and azides under mild reaction conditions. To our knowledge, this is the first study in which this framework was constructed through a multicomponent reaction, which is innovative, efficient and economical. This journal is

Synthesis, Absorption, and Fluorescence Studies of Coumaryl-Labelled Amino Acids and Dipeptides Linked Via Triazole Ring

Fluorophores based on 4-triazolyl, 7-hydroxy-4-triazolylmethyl, 4-O-triazolylmethyl, and 7-O-triazolylmethyl coumaryl-tagged amino acids and dipeptides were synthesized by copper-catalyzed [3+2] cycloaddition reaction between azido- or alkynyl-functionalized coumarins with alkynyl- or azido-functionalized amino acid and dipeptides in good-to-excellent yields. Steady-state absorption and the fluorescence properties of the synthesized conjugates were studied. The chemical applicability of these amino acid and peptide-based fluorophores was successfully demonstrated by their linear elongation by further tagging them with appropriate C- or N-terminus amino acid.