116912-10-8

Basic information

• Product Name: L-Leucine, N-[N-(phenylacetyl)-L-phenylalanyl]-, methyl ester
• CAS NO: 116912-10-8
• Molecular Formula: C24H30N2O4
• Molecular Weight: 410.513
• Mol File: 116912-10-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Leucine, N-[N-(phenylacetyl)-L-phenylalanyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, N-[N-(phenylacetyl)-L-phenylalanyl]-, methyl ester(116912-10-8)
• EPA Substance Registry System: L-Leucine, N-[N-(phenylacetyl)-L-phenylalanyl]-, methyl ester(116912-10-8)

Safety Data

• Hazardous Substances Data: 116912-10-8(Hazardous Substances Data)

Upstream product

• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 738-75-0 (S)-3-phenyl-2-phenylacetylamino-propionic acid 
• 2666-93-5 (S)-Leu-OMe 

Downstream Products

• 116912-21-1 N-(Phenylacetyl)-L-phenylalanyl-L-leucin 
• 38155-19-0 L-phenylalanyl-L-leucine methyl ester 

Relevant articles and documents

THE USE OF PENICILLIN ACYLASE FOR SELECTIVE N-TERMINAL DEPROTECTION IN PEPTIDE SYNTHESIS

Penicillin acylase from E. coli (EC 3.5.1.11) accepts a broad range of N-phenylacetyl-dipeptide esters as substrates.The enzyme hydrolyses the N-terminal protecting group selectively at room temp. and pH=8.1 without affecting the peptide- or the ester-bonds.Alternatively methyl-, benzyl-, tert-butyl and allyl esters can be cleaved chemically leaving the phenylacetamido moiety intact.