38155-19-0

Basic information

• Product Name: L-Leucine, L-phenylalanyl-, methyl ester
• CAS NO: 38155-19-0
• Molecular Formula: C16H24N2O3
• Molecular Weight: 292.378
• Mol File: 38155-19-0.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: L-Leucine, L-phenylalanyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, L-phenylalanyl-, methyl ester(38155-19-0)
• EPA Substance Registry System: L-Leucine, L-phenylalanyl-, methyl ester(38155-19-0)

Safety Data

• Hazardous Substances Data: 38155-19-0(Hazardous Substances Data)

Usage

General Description

L-Leucine, L-phenylalanyl-, methyl ester is a chemical compound that is a derivative of the amino acid L-leucine and L-phenylalanine. It is commonly used in the pharmaceutical and biotechnology industries for its potential role in protein synthesis and muscle growth. L-Leucine, L-phenylalanyl-, methyl ester is also known to have antioxidant properties and may play a role in promoting healthy liver function. Additionally, it is used as a flavoring agent in the food industry and as a fragrance ingredient in the cosmetic industry. Overall, L-Leucine, L-phenylalanyl-, methyl ester has several potential applications in various fields due to its unique chemical properties and potential health benefits.

Upstream product

• 64152-76-7 methyl (S)-2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-4-methylpentanoate 
• 738-75-0 (S)-3-phenyl-2-phenylacetylamino-propionic acid 
• 38155-45-2 methyl L-phenylalanyl-L-leucinate hydrochloride 
• 2666-93-5 L-Leucine methyl ester 
• 4530-18-1 N-(tert-butoxycarbonyl)-L-phenylalanine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 1161-13-3 N-Cbz-L-Phe 
• 2666-93-5 (S)-Leu-OMe 
• 186581-53-3 diazomethane 
• 3303-55-7 L-Phe-Leu 
• 67-56-1 methanol 
• 67320-88-1 Z(OMe)-Phe-Leu-OMe 
• 123168-19-4 (S)-2-[(S)-2-(2,7-Di-tert-butyl-10,10-dioxo-9,10-dihydro-10λ⁶-thioxanthen-9-ylmethoxycarbonylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid methyl ester 

Downstream Products

• 137282-21-4 (2S)-2-<<(2S)-2-<(2-hydroxy-2-methylpropyl)amino>-3-phenylpropionyl>amino>-4-methylpentanoic acid methyl ester 
• 183742-81-6 (S)-2-((S)-2-{[(2S,3S,4R,5R,6S)-6-(Benzyloxycarbonylamino-methyl)-3,4,5-trihydroxy-tetrahydro-pyran-2-carbonyl]-amino}-3-phenyl-propionylamino)-4-methyl-pentanoic acid methyl ester 
• 332855-44-4 N-formyl-Met-Ile-Phe-Leu-OMe 
• 332855-41-1 N-isopropylureido-Met-Ile-Phe-Leu-OMe 
• 107941-79-7 (N,N-dioctyl,Leu⁵)enkephalin 
• 107941-92-4 N,N-dipentyl-O-tert-butyltyrosylglycylglycylphenylalanylleucine methyl ester 
• 107941-80-0 (N,N-diphenethyl,Leu⁵)enkephalin 
• 107941-97-9 N-2-phenethyl-O-tert-butyltyrosylglycylglycylphenylalanylleucine methyl ester 
• 107941-98-0 5>enkephalin 
• 107942-01-8 (S)-2-[(S)-2-(2-{2-[(S)-3-(4-tert-Butoxy-phenyl)-2-dioctylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid 
• 107942-02-9 (S)-2-[(S)-2-(2-{2-[(S)-3-(4-tert-Butoxy-phenyl)-2-diphenethylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid 
• 107941-87-7 N,N-dibenzyl-O-tert-butyltyrosylglycylglycylphenylalanylleucine methyl ester 
• 107941-93-5 N,N-dioctyl-O-tert-butyltyrosylglycylglycylphenylalanylleucine methyl ester 
• 107941-94-6 N,N-di-2-phenethyl-O-tert-butyltyrosylglycylglycylphenylalanylleucine methyl ester 

Relevant articles and documents

An effective and safe enkephalin analog for antinociception

Opioids account for 69,000 overdose deaths per annum worldwide and cause serious side effects. Safer analgesics are urgently needed. The endogenous opioid peptide Leu-Enkephalin (Leu-ENK) is ineffective when introduced peripherally due to poor stability a

Synthesis, characterization and antimicrobial activity of protected dipeptides and their deprotected analogs

Peptides are the chemical compounds which consist of amino acids coupled together by peptide linkage. Peptide derivatives are synthesized by coupling the carboxyl group of one amino acid with amino group of other. Due to the possibilities of fortuitous and unintentional reactions, various protecting groups are used to protect the carboxylic acid as well as amino groups of both the amino acids. These peptide derivatives are associated with a variety of pharmacological activities including antibacterial and antifungal activities. While doing our analysis some of the dipeptides were synthesized in a reasonable yield and purity which were fully characterised by FTIR and H1 NMR. The antimicrobial activity of these derivatives was studied and these were found to be active against two strains of fungi (Aspergillus fumigatus & Pencillium chrysogenum) and two strains of bacteria (E. coli and Salmonella typhimurium). This provides for a future insight to work on the synthesis of these dipeptide derivatives to achieve their stability.

Synthesis of novel sugar amino acids by Curtius rearrangement

Sugar amino acids (SAAs) bearing an amine group on the anomeric position are a challenging class of SAAs to synthesize due to the inherent instability of glycosylamines. We developed a novel synthetic strategy towards both furanoid and pyranoid δ-SAAs of