117207-68-8Relevant academic research and scientific papers
REACTIVE CONJUGATES
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Page/Page column 135; 138-139, (2021/06/11)
The present invention relates to compounds (reactive conjugates) for the chemical modification of therapeutic antibodies or proteins. The compounds enable the regioselective attachment of a payload to an antibody or antibody fragment in one single step, t
ω-Conotoxin GVIA mimetics based on an anthranilamide core: Effect of variation in ammonium side chain lengths and incorporation of fluorine
Andersson, Asa,Baell, Jonathan B.,Duggan, Peter J.,Graham, Janease E.,Lewis, Richard J.,Lumsden, Natalie G.,Tranberg, C. Elisabet,Tuck, Kellie L.,Yang, Aijun
experimental part, p. 6659 - 6670 (2009/12/06)
A number of ω-conotoxin GVIA mimetics based on an anthranilamide core were prepared and tested for their affinity for rat brain Cav2.2 channels. Features such as the presence of hydroxyl and fluoro substituents on the tyrosine side chain mimic,
