1172119-72-0

Basic information

• Product Name: C₂₇H₃₄FN₇O₅
• Synonyms: C₂₇H₃₄FN₇O₅
• CAS NO: 1172119-72-0
• Molecular Weight: 555.609
• Mol File: 1172119-72-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₄FN₇O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₄FN₇O₅(1172119-72-0)
• EPA Substance Registry System: C₂₇H₃₄FN₇O₅(1172119-72-0)

Safety Data

• Hazardous Substances Data: 1172119-72-0(Hazardous Substances Data)

Upstream product

• 1172119-89-9 tert-butyl (Z)-[4-(methylamino)but-2-en-1-yl]carbamate 
• 136834-20-3 N-(9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide 
• 5536-17-4 arabinosyl adenine 
• 136834-18-9 N⁶-benzoyl-9-(3,5-di-O-tetrahydropyran-2-yl-β-D-arabinofuranosyl)adenine 
• 98-88-4 benzoyl chloride 
• 123642-28-4 cis-tert-butoxycarbonyl-4-chloro-2-butenyl-1-amine 

Relevant articles and documents

Discovery of new S-adenosylmethionine decarboxylase inhibitors for the treatment of Human African Trypanosomiasis (HAT)

Modification of the structure of trypanosomal AdoMetDC inhibitor 1 (MDL73811) resulted in the identification of a new inhibitor 7a, which features a methyl substituent at the 8-position. Compound 7a exhibits improved potencies against both the trypanosomal AdoMetDC enzyme and parasites, and better blood brain barrier penetration than 1.