1172366-78-7

Basic information

• Product Name: METHYL (6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)ACETATE HYDROCHLORIDE
• Synonyms: METHYL (6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)ACETATE HYDROCHLORIDE;methyl 2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate:hydrochloride
• CAS NO: 1172366-78-7
• Molecular Formula: C₁₄H₁₉NO₄*ClH
• Molecular Weight: 301.77
• Mol File: 1172366-78-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL (6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)ACETATE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL (6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)ACETATE HYDROCHLORIDE(1172366-78-7)
• EPA Substance Registry System: METHYL (6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)ACETATE HYDROCHLORIDE(1172366-78-7)

Safety Data

• Hazardous Substances Data: 1172366-78-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 68345-67-5 2‐(6,7‐dimethoxy‐1,2,3,4‐tetrahydroisoquinolin‐1‐yl)acetic acid 

Relevant articles and documents

AMIDE DERIVATIVES AND DRUGS

The present invention provides an amide derivative represented by the following formula [1]: wherein n represents 0 or 1; X represents CR4 or N; Y represents CR6 or N; Z represents CR7 or N; R1 and R2 may be the same or different and each represents hydrogen, optionally substituted alkyl, acyl, optionally substituted aryl, or an optionally substituted aromatic heterocyclic group; R4, R5, R6 and R7 may be the same or different and each represents hydrogen, halogen, hydroxy, amino, alkyl, haloalkyl, alkoxy, monoalkylamino, dialkylamino, arylalkyl, cyano, or nitro; and R3 represents optionally substituted alkylamino, optionally substituted arylamino, or optionally substituted cyclic amino, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising them as an active ingredient. The compound of the present invention is useful as a TGF-β inhibitor.