117275-33-9Relevant academic research and scientific papers
Preventing protein oxidation with sugars: Scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives
Storkey, Corin,Pattison, David I.,White, Jonathan M.,Schiesser, Carl H.,Davies, Michael J.
, p. 2589 - 2599 (2012)
Heme peroxidases including myeloperoxidase (MPO) are released at sites of inflammation by activated leukocytes. MPO generates hypohalous acids (HOX, X = Cl, Br, SCN) from H2O2; these oxidants are bactericidal and are key components o
Using In(III) as a promoter for glycosylation
Mattson, Amanda L.,Michel, Anna K.,Cloninger, Mary J.
scheme or table, p. 142 - 146 (2012/03/10)
InCl3, InBr3, and In(OTf)3 were tested as promoters in the preparation of glycosides from trichloroacetimidate precursors. A range of protecting groups and of alcohol acceptors were used to determine the versatility of these promoters. Disaccharide formation was demonstrated. In most cases, the In(III) compounds were shown to promote glycosylation better than the widely used promoter BF3·OEt2.
SELENO-COMPOUNDS AND THERAPEUTIC USES THEREOF
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Page/Page column 50-51, (2012/05/19)
The present invention relates to compounds and compositions useful as antioxidants and in particular to selenium containing compounds of formula (I): wherein n is 1, 2, or 3; m is 2, 3, 4, or 5; and each R] is independently -(optionally substituted C 1 -C3 alkylene) p-OH, where p is 0 or 1, or a salt thereof. The invention also relates to the use of these seleno-compounds in the treatment of diseases or conditions associated with increased levels of oxidants produced by myeloperoxidase (MPO), such as for instance, atherosclerosis.
Cationic palladium(II)-catalyzed stereoselective glycosylation with glycosyl trichloroacetimidates
Yang, Jaemoon,Cooper-Vanosdell, Colleen,Mensah, Enoch A.,Nguyen, Hien M.
, p. 794 - 800 (2008/09/18)
(Chemical Equation Presented) The development of a new method for stereoselective glycosylation with glycosyl trichloroacetimidate donors employing cationic palladium(II), Pd(CH3CN)4(BF 4)2, is described. This p
Parasite glycoconjugates. Part 12. Synthesis of deoxy, fluorodeoxy and aminodeoxy disaccharide phosphates, substrate analogues for the elongating α-D-mannopyranosylphosphate transferase in the Leishmania
Yashunsky, Dmitry V.,Tsvetkov, Yury E.,Ferguson, Michael A.J.,Nikolaev, Andrei V.
, p. 242 - 256 (2007/10/03)
A set of phosphodisaccharides, structural analogues of the β-D-galactosyl-(1→4)-α-D-mannosyl phosphate 1, are synthesized using the Koenigs-Knorr method for the glycosylation reactions and the glycosyl hydrogenphosphonate method for phosphorylation. The c
Synthesis and biological activities of (4,6-di-O-phosphonato-β-D-mannopyranosyl)methylphosphonate as an analogue of 1L-myo-inositol 1,4,5-trisphosphate
Chung, Sung-Kee,Moon, Sung-Hwan
, p. 39 - 50 (2007/10/02)
The synthesis of the α and β anomers of the title compound (1) was accomplished from D-mannose.In the key step, the phosphonate analogues of the mannopyranosyl phosphates were prepared by a direct Wadsworth-Emmons condensation of a protected mannose derivative (8) with tetraethyl methylenebisphosphonate under two-phase conditions.In vitro bioassays have shown that the β-anomer (1a) is a potent inhibitor of Ins(1,4,5)P3 3- kinase and inhibits other enzymes.
1,2-DIDEOXY-3,4:5,7-BIS-O-(1-METHYLETHYLIDENE)-D-GLUCO- AND D-GALACTO-HEPT-1-YNITOLS: SYNTHESIS AND CONFORMATIONAL STUDIES.
Mella, Mariella,Panza, Luigi,Ronchetti, Fiamma,Toma, Lucio
, p. 1673 - 1678 (2007/10/02)
1,2-dideoxy-3,4:5,7-bis-O-(1-methylethylidene)-D-gluco- and D-galacto-hept-1-ynitols were synthesized starting respectively from benzyl α,β-D-glucopyranoside and from benzyl α,β-D-galactopyranoside by bis-acetonidation, hydrogenolysis, Wittig reaction wit
