117286-85-8

Basic information

• Product Name: 3-[[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino](4-methoxyphenyl)methyl]-4-methoxybenzenepropanoic acid
• Synonyms: 3-[[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino](4-methoxyphenyl)methyl]-4-methoxybenzenepropanoic acid
• CAS NO: 117286-85-8
• Molecular Formula: C₃₃H₃₁NO₆
• Molecular Weight: 537.6
• Mol File: 117286-85-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 174-175 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
• Boiling Point: 764.1±60.0 °C(Predicted)
• Appearance: /
• Density: 1.246±0.06 g/cm3(Predicted)
• PKA: 4.70±0.10(Predicted)
• CAS DataBase Reference: 3-[[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino](4-methoxyphenyl)methyl]-4-methoxybenzenepropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino](4-methoxyphenyl)methyl]-4-methoxybenzenepropanoic acid(117286-85-8)
• EPA Substance Registry System: 3-[[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino](4-methoxyphenyl)methyl]-4-methoxybenzenepropanoic acid(117286-85-8)

Safety Data

• Hazardous Substances Data: 117286-85-8(Hazardous Substances Data)

Upstream product

• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 117286-84-7 3-{3-[[(E)-Hydroxyimino]-(4-methoxy-phenyl)-methyl]-4-methoxy-phenyl}-propionic acid 
• 123795-50-6 3-[4-Methoxy-3-(4-methoxy-benzoyl)-phenyl]-propionic acid 
• 100-07-2 4-methoxy-benzoyl chloride 
• 117286-83-6 methyl 3-(4-methoxybenzoyl)-4-methoxyphenylpropionate 
• 15823-04-8 methyl 3-(4-methoxyphenyl)propionate 
• 117286-86-9 3-(3-(amino-4-methoxyphenylmethyl)-4-methoxyphenyl)propionic acid 

Relevant articles and documents

Benzhydrylamine derivatives

Novel benzhydrylamine derivatives represented by general formulas (I) and (II) are useful as reaction reagents for the solid-phase synthesis of polypeptide amides making use of 9-fluorenylmethyloxycarbonyl group ("Fmoc"). An intermediate for these derivat

A MODIFIED BENZHYDRYLAMINE - A USEFUL HANDLE REAGENT FOR Fmoc BASED SOLID PHASE SYNTHESIS OF PEPTIDE AMIDES

Usefulness of a dimethoxybenzhydrylamine derivative, 3-(3-(Fmoc-amino-4-methoxyphenylmethyl)-4-methoxyphenyl)propionic acid, for Fmoc-based solid phase synthesis of peptide amides was demonstrated by preparation of three biologically active peptide amides, i.e. tetragastrin, neuromedin B and vasopressin. 1M trimethylsilyl bromide-thioanisole (molar ration 1 : 1) in trifluoroacetic acid was recommended as a deprotecting reagent for releasing the peptide amides from the resin.