1173102-57-2Relevant academic research and scientific papers
Chemodosimeter for fluoride ions based on F--triggered Si-O cleavage followed by the deprotonation/autoxidation of secondary nitrile C-H group
Li, Baiyun,Zhang, Chuanxiu,Liu, Chuanxiang,Chen, Jinju,Wang, Xinyu,Liu, Zhenjiang,Yi, Fengping
, p. 46016 - 46019 (2014)
A completely new strategy for a chemodosimeter for fluoride based on F--triggered Si-O bond cleavage, followed by the deprotonation/autoxidation of secondary nitrile C-H group was developed for the first time. The chemodosimeter exhibited high selectivity and sensitivity, dramatic color turn-on , and fluorescence turn-off for the detection for fluoride.
Versatile and fluoride-free cyanation of alkyl halides and sulfonates with trimethylsilyl cyanide
Yabe, Osamu,Mizufune, Hideya,Ikemoto, Tomomi
experimental part, p. 1291 - 1294 (2009/10/23)
Cyanation of biphenyl-4-ylmethyl methanesulfonate with trimethylsilyl cyanide using fluoride-free inorganic salts, such as Cs2CO 3, K2CO3, and LiOH·H2O, as additives in MeCN quantitatively gave biphenyl-4-ylacetonitrile. This methodology was applied to various alkyl halides to give the corresponding nitrile compounds in good to excellent yields. Of note, 4-(hydroxymethyl) benzyliodide O-protected by the silyl group was converted into phenylacetonitrile derivative in 99% yield without desilylation. Georg Thieme Verlag Stuttgart.
