117330-41-3

Upstream product

• 98491-78-2 methyl 6-methyl-2-hydroxypyridine-4-carboxylate 
• 144342-49-4 6,6′-dimethyl-2,2′-bipyridine-4,4′-dicarboxylic acid 
• 144342-48-3 4,4'-Bis(fur-2-yl)-6,6'-dimethyl-2,2'-bipyridine 
• 92152-08-4 (1E,5E)-1,6-di(furan-2-yl)hexa-1,5-diene-3,4-dione 
• 562086-28-6 methyl 2-methyl-6-<(p-toluenesulfonyl)oxy>pyridine-4-carboxylate 
• 117330-40-2 dimethyl 6,6'-dimethyl-2,2'-bipyridine-4,4'-dicarboxylate 

Downstream Products

• 381224-19-7 C₅₀H₅₀N₆O₁₂S₂ 

Relevant academic research and scientific papers

Practical bromination approach to the synthesis of dimethyl 6,6’-bis(Bromomethyl)-[2,2’-bipyridine]-4,4’-dicarboxylate

Dimethyl 6,6’-bis(bromomethyl)-[2,2’-bipyridine]-4,4’-dicarboxylate (2) was synthesized from dimethyl 6,6’-dimethyl-2,2'-bipyridine-4,4'-dicarboxylate (1) through dibromination and debromination. Debromination of dimethyl 6,6’-bis(dibromomethyl)-[2,2’-bip

Preparation method of 6,6'-dibromomethyl-2,2'-bipyridyl-4,4'-dicarboxylic acid dimethyl ester

The invention provides a preparation method of 6,6'-dibromomethyl-2,2'-bipyridyl-4,4'-dicarboxylic acid dimethyl ester. The preparation method comprises the following steps: reacting by virtue of 6,6'-dimethyl-2,2'-bipyridyl-4,4'-dicarboxylic acid dimethyl ester and NBS, and stirring for reaction at 55-65 DEG C for 30-40 hours by taking ALBN as an initiator; and processing to obtain 6,6,6',6'-tetrabromomethyl-2,2'-bipyridyl 4,4'-dicarboxylic acid dimethyl ester, reacting at 20-25 DEG C for 18-22 hours by virtue of 6,6,6',6'-tetrabromomethyl-2,2'-bipyridyl 4,4'-dicarboxylic acid dimethyl esterand tertiary amine substances, and processing, so as to obtain the product, namely 6,6'-dibromomethyl-2,2'-bipyridyl-4,4'-dicarboxylic acid dimethyl ester. The preparation method only comprises two reaction steps, the conditions are simple and feasible, the reaction operation is convenient, byproducts are few and are easily separated, and the practicability of the preparation method is strong.

Lanthanide-series compound and preparation method and application thereof

The invention provides a lanthanide-series compound and a preparation method and an application thereof; the lanthanide-series compound has the chemical structural formula described in the description. The lanthanide-series compound has no inversion center, is beneficial for the compound to generate higher-brightness fluorescence, and enables a strongest emission peak to be used in a fluorescence analysis peak of time-resolved fluorescence immunoassay; and at the same time, the compound has relatively strong stability, and still can be used for marking and testing after being placed for a certain time.

Synthesis and Characterisation of the Sodium and Lithium Cryptates of Macrobicyclic Ligands Incorporating Pyridine, Bipyridine, and Biisoquinoline Units

Synthetic procedures have been developed for the preparation of sodium and lithium cryptates of the macrobicyclic ligands 1-11 containing pyridine, bipyridine, and biisoquinoline groups.They involve stepwise construction of the bicyclic system as well as direct macrobicyclisation procedures (Scheme 1) and give access to both symmetrical and dissymmetrical structures.Marked cation template effects have been found that facilitate the cyclisation processes.The ligands 1-11 were isolated as their cryptates with Na+ or Li+ cations.