1173715-82-6

Basic information

• Product Name: methyl (2S)-4-methylene-1-p-toluenesulfonylpyrroplidine-2-carboxylate
• Synonyms: methyl (2S)-4-methylene-1-p-toluenesulfonylpyrroplidine-2-carboxylate
• CAS NO: 1173715-82-6
• Molecular Weight: 295.359
• Mol File: 1173715-82-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (2S)-4-methylene-1-p-toluenesulfonylpyrroplidine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2S)-4-methylene-1-p-toluenesulfonylpyrroplidine-2-carboxylate(1173715-82-6)
• EPA Substance Registry System: methyl (2S)-4-methylene-1-p-toluenesulfonylpyrroplidine-2-carboxylate(1173715-82-6)

Safety Data

• Hazardous Substances Data: 1173715-82-6(Hazardous Substances Data)

Upstream product

• 84348-41-4 (S)-methyl 4-methylenepyrrolidine-2-carboxylate hydrochloride 
• 98-59-9 p-toluenesulfonyl chloride 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 16217-10-0 N-tosyl-4-oxoproline methyl ester 

Downstream Products

• 34402-78-3 methyl 4-methyl-1H-pyrrole-2-carboxylate 

Relevant articles and documents

Stereoselective synthesis of substituted pyrrolidines

The present invention relates to a halo-lactonization process for the stereoselective preparation of protected 1-(halo-methyl)-3-oxo-2-oxa-5-azabicyclo[2.2.1]heptane derivatives of formula (II) wherein Hal and R1 are as defined in the description. The invention further relates to the novel compounds of formula (II), and to their further transformation to the compounds of formula (III) wherein R1, R2, R3, and R4 are as defined in the description.