117375-15-2

Basic information

• Product Name: 1H-Pyrrolizine-7a(5H)-carboxylicacid,tetrahydro-,methylester(9CI)
• Synonyms: 1H-Pyrrolizine-7a(5H)-carboxylicacid,tetrahydro-,methylester(9CI);tetrahydro-1H-Pyrrolizine-7a(5H)-carboxylic acid Methyl ester;Methyl hexahydro-1H-pyrrolizine-7a-carboxylate;1H-Pyrrolizine-7a(5H)-carboxylic acid, tetrahydro-, Methyl ester;Methyl tetrahydro-1H-pyrrolizine-7a(5H)-carboxylate
• CAS NO: 117375-15-2
• Molecular Formula: C9H15NO2
• Molecular Weight: 169.23
• Product Categories: PYRROLE
• Mol File: 117375-15-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 213.6±23.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 8.82±0.40(Predicted)
• CAS DataBase Reference: 1H-Pyrrolizine-7a(5H)-carboxylicacid,tetrahydro-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolizine-7a(5H)-carboxylicacid,tetrahydro-,methylester(9CI)(117375-15-2)
• EPA Substance Registry System: 1H-Pyrrolizine-7a(5H)-carboxylicacid,tetrahydro-,methylester(9CI)(117375-15-2)

Safety Data

• Hazardous Substances Data: 117375-15-2(Hazardous Substances Data)

Usage

General Description

"1H-Pyrrolizine-7a(5H)-carboxylic acid, tetrahydro-, methyl ester (9CI)" is a complex chemical compound. The compound is linked to the pyrrolizine group, which is a class of organic compounds that are part of the larger alkaloid family. The "1H", "7a(5H)" and "tetrahydro" parts of its name suggest the presence of hydrogen atoms and a degree of saturation in its structure. The methyl ester component suggests it has undergone esterification, a chemical process where an alcohol and a carboxylic acid react. 1H-Pyrrolizine-7a(5H)-carboxylicacid,tetrahydro-,methylester(9CI) could have several potential uses in the field of chemistry or pharmacology, though further research is needed to detail its properties and applications.

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Relevant articles and documents

QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF

Provided herein are novel compounds, for example, compounds having a Formula (I), Formula (II), or Formula (III), or a pharmaceutically acceptable salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting KRAS G12D in a cancer cell, and/or in treating various cancer such as pancreatic cancer, colorectal cancer, lung cancer or endometrial cancer.

FIVE-MEMBERED HETEROAROMATIC OLEFINIC AZACYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS INHIBITORS OF NCOTINIC CHOLINERGIC RECEPTORS

The present invention relates to five-membered heteroaromatic olefinic azacyclic compounds and five-membered heteroaromatic acetylenic azacylic compounds, having formula (I) wherein the ring including X, XI, XII, XIII and X IV is heteroaromatic, B is a two-carbon bridging species and Q, E, EI, EII, EIII, m and n are as defined herein and pharmaceutical compositions containing them that are capable of affecting nicotic cholinergic receptors.

Preparation of 7a-heteroarylhexahydro-1H-pyrrolizines as cholinergic synaptic transmission modulators.

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