909076-34-2

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
1-tert-butyl 2-methyl 2-(3-chloropropyl)pyrrolidine-1,2-dicarboxylate is used as a research compound for exploring its pharmacological properties. Its unique molecular structure allows it to be studied for potential therapeutic applications in medicine.
Used in Organic Synthesis and Chemical Reactions:
In the field of organic synthesis, 1-tert-butyl 2-methyl 2-(3-chloropropyl)pyrrolidine-1,2-dicarboxylate serves as a versatile intermediate or reactant in various chemical reactions. Its functional groups and structural features enable it to participate in a range of synthetic processes, contributing to the development of new organic compounds and materials.
Proper handling and storage are essential for ensuring the safety and effectiveness of 1-tert-butyl 2-methyl 2-(3-chloropropyl)pyrrolidine-1,2-dicarboxylate in its intended applications.

Upstream product

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Relevant academic research and scientific papers

QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF

Provided herein are novel compounds, for example, compounds having a Formula (I), Formula (II), or Formula (III), or a pharmaceutically acceptable salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting KRAS G12D in a cancer cell, and/or in treating various cancer such as pancreatic cancer, colorectal cancer, lung cancer or endometrial cancer.

KRAS G12C INHIBITORS

The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

A α - aza volute apperception preparation method of compound (by machine translation)

The present invention provides a compound of α - aza volute apperception preparation method, with amino protective agent will be proline or 2 - piperidine carboxylic acid derivatives by reduction, oxidation, reductive amination, cyclization and other four-step reaction to obtain the α - aza spiro compound. The method of the invention only need 4 step reaction can be completed target preparation, simple and convenient operation, the four-step high overall yield, is usually 51.5% - 66.7%; to avoid the use of expensive and dangerous reagent, with the value of the large-scale preparation of the synthetic method. (by machine translation)