1174039-97-4

Upstream product

• 120-03-6 2-(p-tolyl)-1H-benzimidazole 
• 20718-17-6 2-(dimethyl(oxo)-λ⁶-sulfaneylidene)-1-phenylethan-1-one 
• 824-54-4 2-bromo-4-methylbenzaldehyde 
• 42872-73-1 4-methyl-2-bromobenzonitrile 
• 1260150-32-0 4-methyl-2-(phenylethynyl)benzonitrile 
• 615-43-0 2-iodophenylamine 
• 1273558-75-0 2-(2-bromo-4-methylphenyl)-1H-benzo[d]imidazole 
• 120-46-7 1,3-diphenylpropanedione 
• 2620-81-7 2-(4-methoxyphenyl)-1H-benzimidazole 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 536-74-3 phenylacetylene 
• 95-54-5 1,2-diamino-benzene 

Relevant academic research and scientific papers

Rhodium-Catalyzed Annulation of 2-Arylimidazoles and α-Aroyl Sulfoxonium Ylides toward 5-Arylimidazo[2,1- a ]isoquinolines

A Rh-catalyzed annulation between 2-aryl-1 -benzo[ d ]imidazoles and α-aroyl sulfoxonium ylides was developed, affording a series of benzimidazo[2,1- a ]isoquinolines in moderate to excellent yields. This procedure proceeded with the sequential ortho C-H functionalization and cyclization, representing a facile and straightforward pathway to access such frameworks.

Selective synthesis of benzo[4,5]imidazo[2,1-a]isoquinolines via copper-catalyzed tandem annulation of alkynylbenzonitriles with 2-Iodoanilines

An efficient copper-catalyzed cascade cyclization reaction for selectively synthesizing a variety of benzo[4,5]imidazo[2,1-a]isoquinoline derivatives has been developed. The reaction features the formation of three different C–N bonds in sequence. In the

An efficient synthesis of 6-arylbenzo[4,5]imidazo[2,1-a] isoquinolines via sequential α-arylation of carbonyl and deacylation catalyzed by CuI

Dibenzoyl methane was found to undergo α-arylation of carbonyl and deacylation reaction with 2-(2-bromophenyl)-1H-benzo[d]imidazoles catalyzed by CuI in the presence of Cs2CO3, and provided an efficient synthesis of 6-arylbenzo[4,5]i

Nucleophilic addition of benzimidazoles to alkynyl bromides/palladium- catalyzed intramolecular C-H vinylation: Synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines

An efficient "one-pot" route for the synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines has been developed via nucleophilic addition of 2-aryl benzimidazoles to alkynyl bromides and subsequent palladium-catalyzed intramolecular C-H vinylation.

One-pot concise syntheses of benzimidazo[2,1-a]isoquinolines by a microwave-accelerated tandem process

Direct, efficient syntheses of the benzimidazo[2,1-a]isoquinoline ring system have been achieved with 2-bromoarylaldehydes, terminal alkynes, and 1,2-phenylenediamines by a microwave-accelerated tandem process in which a Sonogashira coupling, 5-endo cyclization, oxidative aromatization, and 6-endo cyclization can be performed in a single synthetic operation.