1174039-97-4Relevant articles and documents
Rhodium-Catalyzed Annulation of 2-Arylimidazoles and α-Aroyl Sulfoxonium Ylides toward 5-Arylimidazo[2,1- a ]isoquinolines
Yang, Rui,Wu, Xiaopeng,Sun, Song,Yu, Jin-Tao,Cheng, Jiang
, p. 3487 - 3492 (2018/09/04)
A Rh-catalyzed annulation between 2-aryl-1 -benzo[ d ]imidazoles and α-aroyl sulfoxonium ylides was developed, affording a series of benzimidazo[2,1- a ]isoquinolines in moderate to excellent yields. This procedure proceeded with the sequential ortho C-H functionalization and cyclization, representing a facile and straightforward pathway to access such frameworks.
An efficient synthesis of 6-arylbenzo[4,5]imidazo[2,1-a] isoquinolines via sequential α-arylation of carbonyl and deacylation catalyzed by CuI
Miao, Wei-Qing,Liu, Jian-Quan,Wang, Xiang-Shan
, p. 5325 - 5331 (2017/07/10)
Dibenzoyl methane was found to undergo α-arylation of carbonyl and deacylation reaction with 2-(2-bromophenyl)-1H-benzo[d]imidazoles catalyzed by CuI in the presence of Cs2CO3, and provided an efficient synthesis of 6-arylbenzo[4,5]i
One-pot concise syntheses of benzimidazo[2,1-a]isoquinolines by a microwave-accelerated tandem process
Okamoto, Noriko,Sakurai, Keisuke,Ishikura, Minoru,Takeda, Kei,Yanada, Reiko
scheme or table, p. 4167 - 4169 (2009/10/26)
Direct, efficient syntheses of the benzimidazo[2,1-a]isoquinoline ring system have been achieved with 2-bromoarylaldehydes, terminal alkynes, and 1,2-phenylenediamines by a microwave-accelerated tandem process in which a Sonogashira coupling, 5-endo cyclization, oxidative aromatization, and 6-endo cyclization can be performed in a single synthetic operation.
