1273558-75-0

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 7697-27-0 2-bromo-4-methylbenzoic acid 
• 824-54-4 2-bromo-4-methylbenzaldehyde 

Downstream Products

• 1254070-49-9 C₁₇H₁₅BrN₂ 
• 1449011-50-0 1-(2-aminophenyl)-2-(2-bromo-4-methylphenyl)benzimidazole 
• 1449011-42-0 2-(2-bromo-4-methylphenyl)-1-(2-nitrophenyl)benzimidazole 
• 1174039-97-4 3-methyl-6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline 

Relevant academic research and scientific papers

Synthesis of Trinuclear Benzimidazole-Fused Hybrid Scaffolds by Transition Metal-Free Tandem C(sp2)?N Bond Formation under Microwave Irradiation

2-(2-Bromoaryl)- and 2-(2-bromovinyl)benzimidazoles have been coupled and cyclized with 2-methoxy- and 2-aryloxybenzimidazoles as building blocks in the presence of a base under microwave irradiation to give a class of trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]benzo[4,5]imidazo[1,2-c]quinazolines and -pyrimidines, respectively, in good yields. 2-(2-Bromoaryl)- and 2-(2-bromovinyl)imidazoles also reacted with 2-methoxybenzimidazoles in the presence of base under microwave irradiation to give a class of trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]imidazo[1,2-c]quinazolines and -pyrimidines, respectively, in similar yields. This process seems to proceed via an initial C(sp2)-N coupling by an addition-elimination nucleophilic aromatic substitution (SNAr) and subsequent cyclization accompanied by extrusion of alcohols.

Copper-Catalyzed Construction of Trinuclear N-Fused Hybrid Scaffolds Using Cyclic Ureas as New Building Blocks

2-(2-Bromoaryl)- and 2-(2-bromovinyl)-benzimidazoles are coupled and cyclized with cyclic ureas as new building blocks in dimethylformamide in the presence of a catalytic amount of a copper catalyst and a base to give the corresponding trinuclear N-fused

Expeditious synthetic approach and photophysical properties of fluorescent benzimidazo[1,2-d]dibenzo[b,f][1,4]diazepine derivatives

A short and efficient synthetic route to novel benzimidazo[1,2-d]dibenzo[b, f][1,4]diazepines has been developed using a copper catalyzed intramolecular Ullmann type C-N bond forming reaction as a key step. Copper iodide and 1,10-phenanthroline furnished the desired compounds in good yield. The products are intensely fluorescent with appreciably long lifetimes. Looking at their prospective use as markers for biomacromolecules and in biochemical analysis, we have explored the photophysical properties of these compounds. The spectrophotometric and spectrofluorometric studies reveal that while the absorbance maxima of the compounds are in the UV region, the emission maxima fall in the visible (blue-green) region.

Synthesis of substituted benzimidazo[2,1-a]isoquinolines and its condensed analogues using Pd(0)-catalyzed cyclization/C-H activation

An efficient route for the synthesis of benzimidazo[2,1-a]isoquinolines and its condensed analogues has been developed via the palladium-catalyzed cyclization/C-H activation of N-allyl and N-methallyl derivatives of benzimidazoles.