1174130-81-4

Basic information

• Product Name: N,N-dimethylformamide di-tert-pentoxyacetal
• Synonyms: N,N-dimethylformamide di-tert-pentoxyacetal
• CAS NO: 1174130-81-4
• Molecular Weight: 231.379
• Mol File: 1174130-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-dimethylformamide di-tert-pentoxyacetal(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethylformamide di-tert-pentoxyacetal(1174130-81-4)
• EPA Substance Registry System: N,N-dimethylformamide di-tert-pentoxyacetal(1174130-81-4)

Safety Data

• Hazardous Substances Data: 1174130-81-4(Hazardous Substances Data)

Upstream product

• 1071-38-1 N,N,N',N'-Tetramethylformamidinium chloride 
• 14593-46-5 sodium tert-pentoxide 

Downstream Products

• 1174130-65-4 (R)-5-biphenyl-4-ylmethyl-3-[1-dimethylaminometh-(E/Z)-ylidene]-2-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

NEW PROCESSES

The invention relates to a new process for producing NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone. In detail, the new processes, according to the present invention, are ultimately related to the synthesis of intermediates to prepare the above NEP inhibitors, namely compounds according to formula (1), or salt thereof, wherein R1 and R2 are, independently of each other, hydrogen or a nitrogen protecting group, and R3 is a carboxyl group or an ester group, preferably carboxyl group or alkyl ester.