117417-10-4Relevant academic research and scientific papers
Facile and stereoselective synthesis of (E)-vinyl bromides by microwave-induced reaction of 1,1-dibromoalkenes using a diethyl phosphonate/EtONa/EtOH system
Kuang, Chunxiang,Senboku, Hisanori,Tokuda, Masao
, p. 1491 - 1496 (2002)
(E)-Vinyl bromides were readily prepared from 1,1-dibromoalkenes by microwave irradiation within 1 min using a diethyl phosphonate/EtONa/EtOH system. This method utilizes cheap and environmentally friendly reagents, requires only a short reaction time, and gives (E)-vinyl bromides in high stereoselectivities and high yields.
Palladium(0) Catalyzed Coupling of trans-1,2-Bis(tri-n-butylstannyl)ethylene with Aromatic Halides: A convenient Synthesis of Substituted trans-β-Bromostyrenes
Haack, Richard A.,Penning, Thomas D.,Djuric, Stevan W.,Dziuba, John A.
, p. 2783 - 2786 (2007/10/02)
trans-β-Bromostyrenes have been conveniently prepared in moderate to high yield in a one-pot two-step sequence. trans-1,2-Bis(tri-n-butylstannyl)ethylene underwent a smooth palladium(0) catalyzed coupling reaction with 0.5 equivalents of aromatic bromide or iodide to furnish a trans-β-stannylstyrene.This intermediate vinyl stannane, without isolation, was then converted to the substituted trans-bromostyrene on treatment with molecular bromine.
