1174749-44-0

Basic information

• Product Name: (S)-3-(3-chlorophenyl)-1,3-dimethylindolin-2-one
• Synonyms: (S)-3-(3-chlorophenyl)-1,3-dimethylindolin-2-one
• CAS NO: 1174749-44-0
• Molecular Weight: 271.746
• Mol File: 1174749-44-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-3-(3-chlorophenyl)-1,3-dimethylindolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(3-chlorophenyl)-1,3-dimethylindolin-2-one(1174749-44-0)
• EPA Substance Registry System: (S)-3-(3-chlorophenyl)-1,3-dimethylindolin-2-one(1174749-44-0)

Safety Data

• Hazardous Substances Data: 1174749-44-0(Hazardous Substances Data)

Upstream product

• 24438-17-3 1,3-dimethylindolin-2-one 
• 108-37-2 1-bromo-3-chlorobenzene 
• 1878-65-5 3-chlorophenylacetic acid 
• 53088-68-9 methyl 3-chlorophenylacetate 
• 64123-83-7 methyl 2-(3-chlorophenyl)acrylate 
• 107473-99-4 2-(3-chlorophenyl)acrylic acid 
• 95-55-6 2-amino-phenol 
• 69589-21-5 O-tert-butyldimethylsilyl-2-aminophenol 

Downstream Products

• 1174749-61-1 3-(3-(2,5-dimethylphenylamino)phenyl)-1,3-dimethylindolin-2-one 

Relevant articles and documents

Water as a Hydride Source in Palladium-Catalyzed Enantioselective Reductive Heck Reactions

Pd-catalyzed intramolecular asymmetric carbopalladation of N-aryl acrylamides followed by reduction of C(sp3)-Pd intermediate using diboron–water as a hydride source afforded enantioenriched 3,3-disubstituted oxindoles in high yields and enantioselectivities. When heavy water was used as a deuterium donor in combination with bis(catecholato)diboron (Cat2B2), deuterium was incorporated into the products with high synthetic efficiency. The ligand determined both the enantioselectivity of the reaction and the reaction pathways, thereby affording either hydroarylation (reductive Heck) or carboborylation products.