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117488-23-0 Usage

Biological Activity

Very potent and selective NMDA agonist. Certain confusion exists over the naming of 1-AMINOCYCLOBUTANE-CIS-1,3-DICARBOXYLIC ACID because of apparent contradictions in the literature. This is the isomer which has the carboyxlic acid and the amino groups on opposite sides of the cyclobutyl ring.

Check Digit Verification of cas no

The CAS Registry Mumber 117488-23-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,4,8 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 117488-23:
(8*1)+(7*1)+(6*7)+(5*4)+(4*8)+(3*8)+(2*2)+(1*3)=140
140 % 10 = 0
So 117488-23-0 is a valid CAS Registry Number.

InChI:InChI=1/C6H9NO4/c7-6(5(10)11)1-3(2-6)4(8)9/h3H,1-2,7H2,(H,8,9)(H,10,11)

117488-23-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-AMINOCYCLOBUTANE-CIS-1,3-DICARBOXYLIC ACID

1.2 Other means of identification

Product number	-
Other names	trans-1-aminocyclobutane-1,3-dicarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:117488-23-0 SDS

117488-23-0Upstream product

117488-23-0Downstream Products

117488-23-0Relevant academic research and scientific papers

Synthesis, NMDA receptor antagonist activity, and anticonvulsant action of 1-aminocyclobutanecarboxylic acid derivatives

Gaoni,Chapman,Parvez,Pook,Jane,Watkins

, p. 4288 - 4296 (2007/10/02)

A range of cis- and trans-3-substituted 1-aminocyclobutane-1-carboxylic acids has been synthesized and evaluated for antagonism at excitatory amino acid receptor sites and for anticonvulsant activity. Potent and selective antagonist activity at N-methyl-D

Synthesis and Activity of a Potent N-Methyl-D-aspartic Acid Agonist, trans-1-Aminocyclobutane-1,3-dicarboxylic Acid, and Related Phosphonic and Carboxylic Acids

Allan, Robin D.,Hanrahan, Jane R.,Hambley, Trevor W.,Johnston, Graham A. R.,Mewett, Kenneth N.,Mitrovic, Ann D.

, p. 2905 - 2915 (2007/10/02)

We report the synthesis of a series of 3-carboxy-, 3-(carboxymethyl)-, 3-(1o-phosphoalkenyl)-, and 3-(1o-phosphonoalkyl)-1-aminocyclobutane-1-carboxylic acids for evaluation as agonists or antagonists of neurotransmission at excitatory amino acid receptor

REGIOSPECIFIC ADDITIONS OF HYDRAZOIC ACID AND BENZYLAMINE TO 1-(ARYLSULFONYL)BICYCLOBUTANES. APPLICATION TO THE SYNTHESIS OF CIS AND TRANS 2,7-METHANOGLUTAMIC ACIDS

Gaoni, Yehiel

, p. 1591 - 1594 (2007/10/02)

Addition of hydrazoic acid or benzylamine to 1-(arylsulfonyl)bicyclobutanes introduces the nitrogen nucleophile at position 3 of the derived cyclobutane, even when a carboxyl derivative is present at this position as a second activating group.Precursors o

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