1175675-65-6Relevant articles and documents
NOVEL TRICYCLIC COMPOUND AS IRAK4 INHIBITOR
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, (2021/10/02)
The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases or tumors, containing, as an active ingredient, a tricyclic compound represented by the following Chemical Formula 1 or a pharmaceutically acceptable salt thereof, and a health food composition for preventing or alleviating autoimmune diseases or tumors, containing the tricyclic compound as an active ingredient. The tricyclic compound represented by Chemical Formula 1 of the present invention has an excellent inhibitory activity against IRAK4, and thus can be usefully used for the prevention, treatment, or alleviation of autoimmune diseases or tumors.
Chemoselective functionalization of α-carbolines at the C-2, C-3, C-4, and C-6 positions using Suzuki-Miyaura reactions
Schneider, Cédric,Gueyrard, David,Joseph, Beno?t,Goekjian, Peter G.
experimental part, p. 5427 - 5437 (2009/11/30)
The synthesis of 2-, 3-, 4-, and 6-substituted pyrido[2,3-b]indoles (α-carbolines) by palladium-catalyzed cross-coupling reactions from the corresponding halopyrido[2,3-b]indoles is described. A sequential and a one-pot chemoselective double Suzuki-Miyaur