1175675-65-6

Upstream product

• 1175675-60-1 6-bromo-4-chloro-9-H-pyrido[2,3-b]indole 
• 98-09-9 benzenesulfonyl chloride 
• 25208-32-6 4-chloro-9-H-pyrido[2,3-b]indole 

Downstream Products

• 1175675-75-8 9-benzenesulfonyl-4-chloro-6-(styryl)-9H-pyrido[2,3-b]indole 
• 1175675-82-7 9-benzenesulfonyl-6-(4-methoxyphenyl)-4-styryl-9H-pyrido[2,3-b]indole 
• 1175675-71-4 9-benzenesulfonyl-4-chloro-6-(4-methoxyphenyl)-9H-pyrido[2,3-b]indole 
• 1175675-91-8 9-benzenesulfonyl-4,6-di(4-methoxyphenyl)-9H-pyrido[2,3-b]indole 

Relevant academic research and scientific papers

NOVEL TRICYCLIC COMPOUND AS IRAK4 INHIBITOR

The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases or tumors, containing, as an active ingredient, a tricyclic compound represented by the following Chemical Formula 1 or a pharmaceutically acceptable salt thereof, and a health food composition for preventing or alleviating autoimmune diseases or tumors, containing the tricyclic compound as an active ingredient. The tricyclic compound represented by Chemical Formula 1 of the present invention has an excellent inhibitory activity against IRAK4, and thus can be usefully used for the prevention, treatment, or alleviation of autoimmune diseases or tumors.

Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl

The present invention relates to compounds of formula (I) wherein R1, R2 and R3 are as defined in the description, to their pharmaceutical compositions and use thereof for the treatment of cancer expressing oncogenic ALK protein, particularly anaplastic l

Chemoselective functionalization of α-carbolines at the C-2, C-3, C-4, and C-6 positions using Suzuki-Miyaura reactions

The synthesis of 2-, 3-, 4-, and 6-substituted pyrido[2,3-b]indoles (α-carbolines) by palladium-catalyzed cross-coupling reactions from the corresponding halopyrido[2,3-b]indoles is described. A sequential and a one-pot chemoselective double Suzuki-Miyaur