1175675-71-4

Upstream product

• 1175675-65-6 9-benzenesulfonyl-6-bromo-4-chloro-9H-pyrido[2,3-b]-indole 
• 5720-07-0 4-methoxyphenylboronic acid 

Downstream Products

• 1175675-82-7 9-benzenesulfonyl-6-(4-methoxyphenyl)-4-styryl-9H-pyrido[2,3-b]indole 

Relevant academic research and scientific papers

Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl

The present invention relates to compounds of formula (I) wherein R1, R2 and R3 are as defined in the description, to their pharmaceutical compositions and use thereof for the treatment of cancer expressing oncogenic ALK protein, particularly anaplastic l

Chemoselective functionalization of α-carbolines at the C-2, C-3, C-4, and C-6 positions using Suzuki-Miyaura reactions

The synthesis of 2-, 3-, 4-, and 6-substituted pyrido[2,3-b]indoles (α-carbolines) by palladium-catalyzed cross-coupling reactions from the corresponding halopyrido[2,3-b]indoles is described. A sequential and a one-pot chemoselective double Suzuki-Miyaur