117649-25-9

Upstream product

• 1624-53-9 2-(benzylideneamino)phenol 
• 1707159-25-8 2-(4-cyanobenzylideneamino)phenol 
• 1761-56-4 2-[[(2-hydroxyphenyl)imino]methyl]phenol 
• 117649-29-3 2-(4-methoxybenzylideneamino)phenol 
• 1624-49-3 2-(4-dimethylamino-benzylidenamino)-phenol 
• 21646-74-2 1-nitro-2-(4-nitrophenyl)-1-ethoxycarbonylethene 
• 95-55-6 2-amino-phenol 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 840-58-4 2(4-nitrophenyl)benzoxazole 
• 1005495-49-7 (2S)-1-(2-hydroxyphenyl)-2-(4-nitrophenyl)-5-methyl-2,3-dihydro-1H-pyridin-4-one 
• 199463-93-9 Ru((C₅H₄N)2)2(OC₆H₄NCHC₆H₄NO₂)⁽¹⁺⁾*ClO₄^(1-)=[Ru((C₅H₄N)2)2(OC₆H₄NCHC₆H₄NO₂)]ClO₄ 
• 909554-15-0 [(N-(2'-hydroxyphenyl)-4-nitrobenzaldimine(-2H))(triphenylphosphine)2RhCl] 

Relevant academic research and scientific papers

Features of the reactions of β-Aryl(heteryl)-α-nitroacrylates with N,N-, N,O-, and N,S-Binucleophiles

The reactions of β-aryl(heteryl)-α-nitroacrylates with N,N-, N,O-, and N,S-binucleophiles proceed regiospecifically through the initial formation of the AdN products, among which only the product from oaminothiophenol was isolated. The conditions of converting the S-adducts into 2-aryl(heteryl)benzothiazole were found. The N-adducts formed in the reaction with hydrazine, o-phenylenediamine, and o-aminophenol undergo immediately the spontaneous transformation into the linear (azine, azomethine) or heterocyclic (benzimidazole) structures. Pleiades Publishing, Ltd., 2012.

Synthesis and biological activities of 2-aminophenol-based Schiff bases and their structure-activity relationship

Six Schiff bases 8-13 were synthesized by condensation of 2-aminophenol (1) with various chloro- and nitro-benzaldehydes (2-7), characterized, and evaluated for antioxidant, antibacterial, lipoxygenase, and urease inhibitory potentials. All Schiff bases e

Copper(II) nitroaromatic Schiff base complexes: Synthesis, biological activity and their interaction with DNA and albumins

Copper(II) complexes of the Schiff base ligands 2-((5-nitrofuran-2-yl)methyleneamino) phenol (HL1) and 2-(4-nitrobenzylideneamino)phenol (HL2) were prepared and characterized using physicochemical and spectroscopic techniques. In these complexes the Schif

Dual colorimetric receptor with logic gate operations: Anion induced solvatochromism

A receptor R1 was designed and synthesised for colorimetric detection of F- ions as well as Cu2+ ions via intramolecular charge transfer mechanism. Upon addition of F- ions in dry DMSO, the color of the receptor R1 changed

A DFT and experimental study of the spectroscopic and hydrolytic degradation behaviour of some benzylideneanilines

The spectroscopic and hydrolytic degradation behaviour of some N-benzylideneanilines are investigated experimentally and theoretically via high quality density function theoretical (DFT) modelling techniques. Their absorption and vibrational spectra, accurately predicted by DFT calculations, are highly dependent on the nature of the substituents on the aromatic rings, hence, though some of their spectroscopic features are similar, energetic differences exist due to differences in their electronic structures. Whereas the o-hydroxy aniline derived adducts undergo hydrolysis via two pathways, the most energetically economical of which is initiated by a fast enthalpy driven hydration, over a conservative free energy (ΔG?) barrier of 53 kJ mol?1, prior to the rate limiting entropy controlled lysis step which occurs via a conservative barrier of ca.132 kJ mol?1, all other compounds hydrolyse via a slower two-step pathway, limited by the hydration step. Barriers heights for both pathways are controlled primarily by the structure and hence, stability of the transition states, all of which are cyclic for both pathways.

A Green, Scalable, One-Minute Synthesis of Benzimidazoles

Herein is reported a substantially improved synthesis of 2-substituted benzimidazoles by condensation of 1,2-diaminoarenes and aldehydes using methanol as the reaction medium. The developed method afforded moderate to excellent yields (33-96percent) at am

Catalyst-free allylation of 2-aminophenol–derived aldimines with allyltrichlorosilane under thermal conditions

Allylation of 2-aminophenol-derived aldimines using allyltrichlorosilane under catalyst free conditions has been developed. This reaction afforded the corresponding homoallylic amines in good to excellent yields (68–94%). The salicylaldehyde-derived aldimines as well as benzoylhydrazone also found to react with allyltrichlorosilane smoothly under the same conditions, to furnish the corresponding homoallylic amine derivatives. This study suggests that the phenolic –OH group acts as an anchoring group for the transfer of allyl group from allyl silane reagent.

Abnormal effect of hydroxyl on the longest wavelength maximum in ultraviolet absorption spectra for bis-aryl Schiff bases

Two sets of bis-aryl Schiff bases that contain 4(or 4′)-OH and 2(or 2′)-OH were synthesized. The first set consists of 4-HOArCH=NArY and XArCH=NArOH-4′, and the second set consists of 2-HOArCH=NArY and XArCH=NArOH-2′. Their ultraviolet absorption spectra were measured and investigated. A very interesting phenomenon was observed by analyzing their wave number νmax (cm?1) of longest wavelength maximum λmax (nm) of ultraviolet. Compared with the change regularity of the νmax of XArCH=NArY (where the X and Y excluded OH), the 4′-position hydroxyl (4′-OH) and 2′-position hydroxyl (2′-OH) have abnormal performance. The details are the following: the 4′-OH contributes an additional red shift to the νmax of XArCH=NArOH-4′ (λmax increase), whereas the 2′-OH contributes an additional blue shift to the νmax of XArCH=NArOH-2′ (λmax decrease). In addition, there are ortho steric effects of all 2-OH and 2′-OH on the νmax for 2-HOArCH=NArY and XArCH=NArOH-2′, and the ortho steric effect contributes a red shift to their νmax. These experimental facts can provide an important theoretical reference for us using aryl Schiff base compounds as optical materials and performing the molecular design.

P-nitrobenzaldehyde Schiff base derivative as well as preparation method and application thereof

The invention discloses a p-nitrobenzaldehyde Schiff base derivative as well as a preparation method and an application thereof. The p-nitrobenzaldehyde Schiff base derivative has a structural formula shown in the specification. During preparation, a cert

Base-Free and Catalyst-Free Synthesis of Functionalized Dihydrobenzoxazoles via Vinylogous Carbonate to Carbamate Rearrangement

An unexpected, catalyst-free, and base-free intramolecular cyclization of N-aryloxyacrylate aldimines, under thermal conditions leading to the synthesis of functionalized dihydrobenzoxazoles, is reported. The reaction features a unique rearrangement of vi