1624-49-3Relevant articles and documents
A small molecule that displays marked reactivity toward copper-versus zinc-amyloid-β implicated in Alzheimer's disease
Savelieff, Masha G.,Liu, Yuzhong,Senthamarai, Russell R.P.,Korshavn, Kyle J.,Lee, Hyuck Jin,Ramamoorthy, Ayyalusamy,Lim, Mi Hee
, p. 5301 - 5303 (2014)
Alzheimer's disease (AD) is a complex, multifactorial, neurodegenerative disease that poses tremendous difficulties in pinpointing its precise etiology. A toolkit, which specifically targets and modulates suggested key players, may elucidate their roles i
Synthesis, spectroscopic characterization, computational studies, theoretical investigation of NLO properties and antibacterial activities of mixed ligand complexes of Co(II) and Cu(II)
Anjum, Afreen,Jaiswal, Nitesh,Kumar, Manoj,Modanawal, Vishnu Kumar,Paswan, Sikandar,Srivastava, Shekhar
, (2022/01/14)
The reaction of Schiff base 2-(4-(dimethylamino)benzylideneamino)phenol (DBAP) and diethylenetriamine/ethylenediamine with cobalt(II) and copper(II) metal ion in equimolar ratio afforded mixed ligand complexes [M(DBAP)(L)Cl(H2O)n] (1
Oxidative NHC Catalysis for the Generation of Imidoyl Azoliums: Synthesis of Benzoxazoles
Patra, Atanu,James, Anjima,Das, Tamal Kanti,Biju, Akkattu T.
, p. 14820 - 14826 (2019/01/03)
N-Heterocyclic carbene (NHC)-catalyzed intramolecular cyclization of aldimines generated from 2-amino phenols and aromatic aldehydes leading to the synthesis of 2-arylbenzoxazoles under mild conditions is presented. The reaction proceeds via the generation of the aza-Breslow intermediates from imines and NHC, which under oxidative conditions form the key imidoyl azoliums and a subsequent intramolecular cyclization furnishes the product. The reaction tolerates a broad range of functional groups, and the products are formed in generally good yields.