1176948-72-3Relevant academic research and scientific papers
Mesoionic pyrido[1,2-a]pyrimidinones: A novel class of insecticides inhibiting nicotinic acetylcholine receptors
Zhang, Wenming,Holyoke, Caleb W.,Barry, James,Leighty, Robert M.,Cordova, Daniel,Vincent, Daniel R.,Hughes, Kenneth A.,Tong, My-Hanh T.,McCann, Stephen F.,Xu, Ming,Briddell, Twyla A.,Pahutski, Thomas F.,Lahm, George P.
, p. 5444 - 5449 (2016/11/11)
A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptional insecticidal activity controlling a number of insect species, particularly hemiptera and lepidoptera. Mode-of-action studies showed that they act on nicotinic acetylcholine receptors (nAChRs) primarily as inhibitors. Here we report the discovery, evolution, and preparation of this class of chemistry. Our efforts in structure–activity relationship elucidation and biological activity evaluation are also presented.
MIXTURES OF MESOIONIC PESTICIDES
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Page/Page column 30, (2011/02/24)
Disclosed are compositions comprising (a) at least one compound selected from compounds of Formula (1), N-oxides, and salt thereof, wherein R1 is phenyl optionally substituted with up to 5 substituents independently selected from R3,
MESOIONIC PESTICIDES
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Page/Page column 70, (2009/10/09)
Disclosed are compounds of Formula 1, wherein X is O or S; Y is O or S; and R1, R2, R3 and R4 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods f
