117718-85-1 Usage
Description
6-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine is a chemical compound with the molecular formula C7H7BrN4. It is a derivative of imidazo[1,2-a]pyrazin-8-amine, a heterocyclic compound frequently utilized in pharmaceutical research and drug development. This specific compound features a bromine atom and a methyl group attached to the imidazo[1,2-a]pyrazin-8-amine core, making it a key building block in the synthesis of biologically active molecules and potential drug candidates. Its unique chemical and biological properties render it a valuable intermediate in the production of pharmaceuticals and other organic compounds.
Uses
Used in Pharmaceutical Research and Drug Development:
6-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine is used as a building block for the synthesis of biologically active molecules and potential drug candidates. Its unique chemical and biological properties make it a valuable intermediate in the development of new pharmaceuticals and organic compounds.
Used in Organic Chemistry:
In the field of organic chemistry, 6-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine is used as a versatile intermediate for the synthesis of a variety of organic compounds. Its structural features, including the bromine atom and the methyl group, facilitate its use in numerous chemical reactions, contributing to the creation of diverse chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 117718-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,7,1 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 117718-85:
(8*1)+(7*1)+(6*7)+(5*7)+(4*1)+(3*8)+(2*8)+(1*5)=141
141 % 10 = 1
So 117718-85-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BrN4/c1-9-6-7-10-2-3-12(7)4-5(8)11-6/h2-4H,1H3,(H,9,11)
117718-85-1Relevant articles and documents
Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhbitors
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Page 56-57, (2010/02/09)
The present invention relates to 8-amino-aryl-substituted imidazopyrazines which modulate the activity of protein kinases (“PKs”). The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
Synthesis and Antibronchospastic Activity of 8-Alkoxy- and 8-(Alkylamino)imidazopyrazines
Bonnet, Pierre A.,Michel, Alain,Laurent, Florence,Sablayrolles, Claire,Rechencq, Eliane,et al.
, p. 3353 - 3358 (2007/10/02)
Theophylline still occupies a dominant place in asthma therapy.Unfortunatly its adverse central nervous system (CNS) stimulant effects can dramatically limit its use, and adjustments in the dosage are often needed.We have synthesized a new series of imidazopyrazine derivatives which are much more potent bronchodilators than theophylline in vivo and do not exhibit the CNS stimulatory profile.In vitro studies on isolated rat uterus and guinea pig trachea confirm the high potentialities of these derivatives. 6-Bromo-8-(methylamino)imidazopyrazine-3-carbonitrile (23) is identified as the most potent compound of the series.As i n the case of theophylline, phosphodiesterase inhibition appears unlikely to be the unique mechanism of the action of this series of heterocycles.
