117738-75-7 Usage
General Description
4-Bromo-3,5-dichlorobenzoic acid is a complex organic compound that features a benzene ring as its core structure, bonded with differing halogen and carboxyl functional groups. The compound is characterized by the presence of one bromine (Br), two chlorine (Cl), and a carboxyl group (-COOH) attached to the benzene ring. This aromatic compound falls under the category of halogenated benzoic acids, often used in the field of organic synthesis, biochemical research, and pharmaceutical development. Its exact properties such as melting point, boiling point, density, and solubility can vary based on different conditions and specific molecular form. Like other halogenated compounds, safe handling and storage are required due to its potential reactivity and toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 117738-75-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,7,3 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 117738-75:
(8*1)+(7*1)+(6*7)+(5*7)+(4*3)+(3*8)+(2*7)+(1*5)=147
147 % 10 = 7
So 117738-75-7 is a valid CAS Registry Number.
117738-75-7Relevant articles and documents
3,5-dichloro-4-bromoisoquinoline derivative, and preparation method and application thereof
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, (2019/10/04)
The invention specifically relates to a novel compound, i.e., a 3,5-dichloro-4-bromoisoquinoline derivative, and a preparation method and application thereof, belonging to the technical field of pharmaceutical synthesis. 3,5-dichloro-4-bromoisoquinoline and the derivative thereof are obtained by ring closure of 3,5-dichloro-4-bromobenzene haloethylamine through a Friedel-Crafts alkylation reaction. The 3,5-dichloro-4-bromoisoquinoline and the derivative can be used for synthesizing the important intermediate 3,5-dichloro-4-carboxylisoquinoline of Lifitegrast. According to a technical scheme in the invention, low-cost and well-supplied 2,6-dichloroaniline is used as a starting material; and the preparation method comprises a plurality steps of reactions with mild conditions, mature operation and yield of 85% or more, and each step of reaction has passed pilot-scale test, so the feasibility of industrial conversion of the method is very high and overall production cost can be greatly reduced.
