117738-76-8

Usage

Uses

4-Chloro-3-cyanobenzoic Acid can be used as antiviral agents.

Upstream product

• 2840-28-0 3-amino-4-chloro-benzoic acid 
• 151-50-8 potassium cyanide 
• 181282-80-4 methyl-3-Cyano-4-chloro-benzoate 
• 773837-37-9 sodium cyanide 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 181282-80-4 methyl-3-Cyano-4-chloro-benzoate 
• 181282-91-7 3-cyano-4-chloro-benzamide 
• 181282-85-9 3-cyano-4-chloro-N,N-dimethylbenzamide 
• 918880-67-8 3-cyano-4-(4-fluorophenoxy)benzoic acid 
• 943732-47-6 tert-butyl 4-(4-chloro-3-cyanobenzoyl)piperazine-1-carboxylate 
• 1261751-27-2 ethyl 4-chloro-3-cyanobenzoate 
• 1444001-66-4 ethyl 4-chloro-3-(N'-hydroxycarbamimidoyl)benzoate 
• 1444001-67-5 ethyl 4-chloro-3-(N'-((ethoxycarbonyl)oxy)carbamimidoyl)benzoate 
• 1444001-65-3 ethyl 4-chloro-3-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)benzoate 
• 1444001-68-6 4-chloro-3-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)benzoic acid 
• 1444001-18-6 (S)-ethyl 1-(4-(5-((4-chloro-3-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)benzamido)methyl)-2-oxooxazolidin-3-yl)phenyl)piperidine-4-carboxylate 
• 918880-71-4 N-(4-hydroxy-5-pyrimidinyl)-4-chloro-3-cyanobenzamide 
• 181282-81-5 dimethyl 3-aminobenzo[b]thiophene-2,5-dicarboxylate 
• 181283-43-2 4-chloro-3-cyanobenzoyl chloride 

Relevant academic research and scientific papers

PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES

Compounds of formula (I) as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control pests such as insect, acarine, mollusc and nematode pests.

Low molecular weight dual inhibitors of factor Xa and fibrinogen binding to GPIIb/IIIa with highly overlapped pharmacophores

Dual antithrombotic agents acting as anticoagulants and aggregation inhibitors could have substantial advantages over currently prescribed combinations of antithrombotic drugs. Herein, we report compounds with moderate inhibitory activity for factor Xa an

CONDENSED PYRIMIDINE DERIVATIVE AND XANTHINE OXIDASE INHIBITOR

The invention relates to compounds of the following formula (I) or their salts: in which R 1 is a group of phenyl, naphthyl, pyridyl or the like which may have a substituent such as an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkoxycarbonyl group having 2-8 carbon atoms, carboxyl, halogen, hydroxyl, nitro, or cyano; R 2 is cyano, nitro, or the like; R 3 is hydroxyl or the like; X is oxygen, sulfur, or the like; and Y is oxygen or sulfur, and a xanthine oxidase inhibitor containing the compound.

P2x7 receptor antagonists for use in the treatment of inflammatory, immune or cardiovascular diseases

The invention provides piperidine compounds of general formula (I) in which A, B, X, Y, Z, R, R1 and R2 are as defined in the specification, their use as medicaments, compositions containing them and processes for their for their preparation.

Structure-activity studies for a novel series of tricyclic substituted hexahydrobenz[e]isoindole α(1A) adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia (BPH)

In search of a uroselective agent that exhibits a high level of selectivity for the α(1A) receptor, a novel series of tricyclic hexahydrobenz[e]isoindoles was synthesized. A generic pharmacophoric model was developed requiring the presence of a basic amine core and a fused heterocyclic side chain separated by an alkyl chain. It was shown that the 6- OMe substitution with R, R stereochemistry of the ring junction of the benz[e]isoindole and a two-carbon spacer chain were optimal. In contrast to the highly specific requirements for the benz[e]isoindole portion and linker chain, a wide variety of tricyclic fused heterocyclic attachments were tolerated with retention of potency and selectivity. In vitro functional assays for the α1 adrenoceptor subtypes were used to further characterize these compounds, and in vivo models of vascular vs prostatic tone were used to assess uroselectivity.

TRICYCLIC SUBSTITUTED HEXAHYDROBENZ [E]ISOINDOLE ALPHA-1 ADRENERGIC ANTAGONISTS

The present invention relates to a compound of the formula STR1 and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an α-1 adrenergic antagonist and is useful in the treatment of BPH; also disclosed are . alpha.-1 antagonist compositions and a method for antagonizing α-1 receptors and treating BPH.

Pesticidal compounds

Bicyclooctane pesticides of the formula are prepared by cyclisation of In these formulae R may be various organic groups and is preferably n-butyl or n-propyl while R2 is a polysubstituted phenyl group.