1177415-90-5

Basic information

• Product Name: ethyl 8-chloro-6-chloroimidazo[1,2-b]pyridazine-3-carboxylate
• Synonyms: ethyl 8-chloro-6-chloroimidazo[1,2-b]pyridazine-3-carboxylate
• CAS NO: 1177415-90-5
• Molecular Weight: 260.079
• Mol File: 1177415-90-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: ethyl 8-chloro-6-chloroimidazo[1,2-b]pyridazine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 8-chloro-6-chloroimidazo[1,2-b]pyridazine-3-carboxylate(1177415-90-5)
• EPA Substance Registry System: ethyl 8-chloro-6-chloroimidazo[1,2-b]pyridazine-3-carboxylate(1177415-90-5)

Safety Data

• Hazardous Substances Data: 1177415-90-5(Hazardous Substances Data)

Upstream product

• 446273-59-2 4-bromo-6-chloro-3-pyridazineamine 
• 33142-21-1 ethyl 2-chloro-3-oxopropanoate 

Downstream Products

• 2098466-94-3 C₁₆H₁₈N₆O 

Relevant articles and documents

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

IMIDAZOPYRIDAZINE MODULATORS OF IL-12, IL-23 AND/OR IFN-ALPHA

Compounds of formula (I) or a stereoisomer or pharmaceutically-acceptable salt thereof, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.