117753-07-8

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-(3-bromophenyl)-N,N-dimethylacetamide serves as a crucial intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure allows it to participate in a range of organic reactions, facilitating the development of new and improved drugs and pesticides.
Used as a Solvent in Chemical Processes:
Due to its polar and nonpolar characteristics, 2-(3-bromophenyl)-N,N-dimethylacetamide is utilized as a solvent in various chemical processes. It aids in the dissolution and interaction of different compounds, enhancing the efficiency and effectiveness of these processes.
Used in the Production of Dyes and Pigments:
2-(3-bromophenyl)-N,N-dimethylacetamide is also employed in the manufacturing of dyes and pigments. Its chemical properties make it suitable for use in the creation of a wide array of colorants for different applications.
Used in Specialty Chemicals Production:
2-(3-bromophenyl)-N,N-dimethylacetamide finds application in the production of specialty chemicals, which are often used in specific industries for unique purposes. Its versatility and reactivity contribute to the development of tailored chemical products.
Safety Considerations:
Given the presence of a bromine substituent in its structure, 2-(3-bromophenyl)-N,N-dimethylacetamide requires careful handling and disposal. It is essential to follow appropriate safety protocols to minimize potential risks associated with its use in chemical processes.

Upstream product

• 1878-67-7 3-Bromophenylacetic acid 
• 84750-92-5 1-bromo-3-(2,2-difluorovinyl)benzene 
• 68-12-2 N,N-dimethyl-formamide 
• 124-40-3 dimethyl amine 

Downstream Products

• 214209-92-4 N,N-dimethyl-2-(3-bromophenyl)ethylamine 
• 93413-93-5 1-[1-(3-bromophenyl)-2-(dimethylamino)ethyl]cyclohexanol 

Relevant academic research and scientific papers

Direct defluorinative amidation-hydrolysis reaction of gem-difluoroalkenes with N,N-dimethylformamide, and primary and secondary amines

A novel and efficient method for the synthesis of arylacetamides by the reactions of gem-difluoroalkenes with N,N-dialkylformamides, and primary and secondary amines with the assistance of KOtBu and water was developed.

Pd-Catalyzed Site-Selective p-Hydroxyphenyloxylation of Benzylic α-C(sp3)-H Bonds with 1,4-Benzoquinone

A Pd-catalyzed, site-selective p-hydroxyphenyloxylation of benzylic α-C(sp3)-H bonds with 1,4-benzoquinone using thioamide as a directing group is reported. 1,4-Benzoquinone is employed as the p-hydroxyphenyloxy source without extra oxidants. T

Pyridine derivatives and pharmaceutical compositions containing them

The invention relates to novel pyridyl derivatives, their use as medicaments, pharmaceutical formulations containing them and methods for their preparation.

2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: Synthesis and antidepressant activity

A series of 2-phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives was examined for the ability to inhibit both rat brain imipramine receptor binding and the synaptosomal uptake of norepinephrine (NE) and serotonin (5-HT). Neurotransmitter uptake inhibition was highest for a subset of 2-phenyl-2-(1-hydroxycyclohexyl)dimethylethylamines in which the aryl ring has a halogen or methoxy substituent at the 3- and/or 4-positions. Potential antidepressant activity in this subset was assayed in three rodent models - the antagonism of reserpine-induced hypothermia, the antagonism of histamine-induced ACTH release, and the ability to reduce noradrenergic responsiveness in the rat pineal gland. An acute effect seen in the rat pineal gland with several analogues, including 1-[1-(3,4-dichlorophenyl)-2-(dimethylamino)ethyl]cyclohexanol (23) and 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol (4), was taken as a possible correlate of a rapid onset of antidepressant activity. Compound 4 (venlafaxine) is presently undergoing clinical evaluation.