117771-01-4Relevant academic research and scientific papers
METAL-DIRECTED ASYMMETRIC SYNTHESIS OF DIASTEREOISOMERIC β-PHENYL SERINES USING (+)-KETOPINIC ACID AS A CHIRAL AUXILIARY.
Casella, Luigi,Jommi, Giancarlo,Montanari, Stefania,Sisti, Massimo
, p. 2067 - 2068 (2007/10/02)
A new method for the asymmetric synthesis of threo and erythro β-phenylserines using (+)-ketopinic acid as a chiral auxiliary is reported.The reaction was based on the condensation of benzaldehyde with the metal (Li+, K+ or Zn++ ) enolates of the chiral imines 3.
