117772-80-2Relevant academic research and scientific papers
Functionalization of an sp3 C-H bond via a redox-neutral domino reaction: Diastereoselective synthesis of hexahydropyrrolo[2,1-b]oxazoles
Rahman, Matiur,Bagdi, Avik Kumar,Mishra, Subhajit,Hajra, Alakananda
, p. 2951 - 2953 (2014)
A diastereoselective synthesis of pyrrolidinooxazolidines was achieved by a metal-free, base-promoted reaction of pyrrolidine and aromatic aldehydes under microwave irradiation. The rare functionalization of an sp3 C-H bond probably results from an in situ generated azomethine ylide that undergoes cycloaddition with aldehydes.
1,3 DIPOLAR CYCLOADDITIONS OF AZOMETHINE YLIDES WITH AROMATIC ALDEHYDES. SYNTHESES OF 1-OXAPYRROLIZIDINES AND 1,3-OXAZOLIDINES.
Orsini, F.,Pelizzoni, F.,Forte, M.,Destro, R.,Gariboldi, P.
, p. 519 - 542 (2007/10/02)
Substituted 1-oxapyrrolizidines have been synthetized by cycloaddition of azomethine ylides, generated by aldehydes induced decarboxylation of proline, with carbonyl dipolarophyles.The stereochemistry of the cycloadducts indicate that they arise from the
