117811-78-6

Basic information

• Product Name: L-ZHPROMSME
• Synonyms: L-ZHPROMSME;N-CARBOBENZYLOXY-4-METHANESULFONYLOXY-L-PROLINE METHYL ESTER;(3R,5S)-1-((benzylo×y)carbonyl)-5-(Metho×ycarbonyl)pyrrolidin-3-yl Methanesulfonate;(2S,4R)-1-Benzyl 2-Methyl 4-((Methylsulfonyl)oxy)pyrrolidine-1,2-dicarboxylate;(3R,5S)-1-((benzyloxy)carbonyl)-5-(Methoxycarbonyl)pyrrolidin-3-yl Methanesulfonate
• CAS NO: 117811-78-6
• Molecular Formula: C₁₅H₁₉NO₇S
• Molecular Weight: 357.39
• Mol File: 117811-78-6.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: L-ZHPROMSME(CAS DataBase Reference)
• NIST Chemistry Reference: L-ZHPROMSME(117811-78-6)
• EPA Substance Registry System: L-ZHPROMSME(117811-78-6)

Safety Data

• Hazardous Substances Data: 117811-78-6(Hazardous Substances Data)

Usage

General Description

L-ZHPROMSME is a mixture of chemicals used in various industrial processes. It contains a combination of lubricants, corrosion inhibitors, cleaning agents, and preservatives, making it a versatile and multifunctional product. The lubricants in L-ZHPROMSME provide a protective film to reduce friction and wear on machinery and equipment, while the corrosion inhibitors help to prevent rust and degradation of metal surfaces. The cleaning agents remove dirt, oil, and other contaminants, ensuring that the equipment remains in optimal condition. Additionally, the preservatives in the mixture help to extend the shelf life of products and materials, making it an essential component for many manufacturing and maintenance operations.

Upstream product

• 64187-48-0 methyl (2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate 
• 501-53-1 benzyl chloroformate 
• 1499-56-5 (R)-4-hydroxy-L-proline ethyl ester 
• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 51-35-4 4R-4-hydroxyproline 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 13504-86-4 (2S,4S)-1-benzyloxycarbonyl-4-hydroxyproline 
• 279-33-4 (1S,4S)-2-oxa-5-aza-bicyclo[2.2.1]heptane 
• 194933-51-2 (2S,4S)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1,2-dicarboxylic acid 1-benzyl-2-methyl 
• 57653-35-7 (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylic acid 1-benzyl 2-methyl 
• 1321614-45-2 N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-(4S)-4-{[(3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoyl]amino}-L-proline 
• 1321614-42-9 methyl N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-(4S)-4-{[(3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoyl]amino}-L-prolinate 
• 1321614-34-9 (4S)-4-{[(3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoyl]amino}-1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline 

Relevant articles and documents

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The invention relates to the technical field of medicines, in particular to an ROR [gamma]t inhibitor, a preparation method and application thereof. The invention also relates to a pharmaceutical composition containing the compound, a method for preparing the pharmaceutical composition, and application of the compound or the pharmaceutical composition in treatment or prevention of ROR [gamma]t-mediated cancers, inflammations or autoimmune diseases of mammals, especially human beings.

COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS

Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.

PHENYL AMINO PYRIMIDINE BICYCLIC COMPOUNDS AND USES THEREOF

The present invention relates to phenyl amino pyrimidine bicyclic compounds formula (I) which are inhibitors of protein kinases including JAK kinases. In particular the compounds are active against JAK1, JAK2, JAK3 and TYK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.